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This paper looks at the biology of the -imods in MS and in relation to COVID-19. It is open access so take your time disgesting it, as it is abit complex. Baker D, Forte E, Pryce G, Kang AS, James LK, Giovannoni G, Schmierer K. The impact of sphingosine-1-phosphate receptor modulators on COVID-19 and SARS-CoV-2 vaccination. Mult Scler Relat Disord. 2022 Nov 22;69:104425. doi: 10.1016/j.msard.2022...
Today I’m Tess (Real or Fake?). Is that Tess of the d’Urbervilles or maybe Tess of the Baskervilles. Yes you can see I will be doing abit of cross dressing for the calendar….isn’t it LBTQ+Dog?
Like other herpes viruses (including EBV which is human herpesvirus 4), VZV is a neurotrophic virus – i.e. it has avidity for neurones. Second to EBV, VZV is the next best infectious contender for causing MS. In this well written case report the paediatricians present a case of new onset MS in a 10 year old following reactivation of herpes zoster which involved the eye. She had chickenpox...
Yesterday I made the point that dogma is not always good for science and that it creates lemmings in science. Whilst I am making myself unpopular with scientists , I may as well go the whole hog and do neurologists today. Fear not they find me irritating anyway. We have been hunting for treatments for progressive disease forever but we do the same trial over and over again, plugging our next...
Today my Name is Bobby….(Fake of Real?).Maybe you know me as Bob..the…rhymes with Bob:-) Better ask ProfA or ProfAngrys’missus for the answer to this one…..I’m Bobby from B………ne. However, he’s the one with the Bike (OK an in Joke). Speaking of which there is still time to put a few Bobs/Quids ProfAs (Click here) way for his Bike Ride round...
As you probably realise, it seems that science is very dogmatic, it is also very sheep-like, possibly through the fear of rejection. It seems as a new scientific-flavour appears because some opinion leader has said this or that, then the masses or a load of lemmings as I call them, follow the head-honcho in an unblinded fashion, sometimes off the cliff (Yes I am a cynic….but without this...
Today by Fake Name is Casanova (Who would name their child casanova?. Of course it’s fake! It would be child abuse….not even Johnny Cash named their child Casanova….but Hey Footballers know they are going to get booked if they take their shirt off…but they still do it….and get sent off…So some people (and rappers) are perhaps stupid enough…..)…Check...
When its spelt wrong. There is a typo in the title it should not be sphinogo
But if you want to learn about fingolimod, siponimod, ponesimod and ozanimod and covid 19
read the article here
The impact of sphingosine-1-phosphate receptor modulators on COVID-19 and SARS-CoV-2 vaccinationhttps://doi.org/10.1016/j.msard.2022.104425
Today my name is Mik or is it Mick/Mike or Michael? (Real or Fake?)
Wonder if Mik is a West Ham fan maybe Charlton Athletic?
Whilst this may be a football chant and so is perhaps approriate as the World Cup is now in full flow, it is part of our new mantra. Whilst ProfK’s native football team has been knocked out and now will have to support his Children’s adopted team at least for a day longer. It is important that we get our clinical colleages to hear and act on this chant as AttackMS is now open for...