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New study testing an upper limb rehab tool – get involved!

The Barts MS team are running a study, investigating whether a new hand and arm activity called “Under & Over” can improve upper limb function for people with MS. The study is titled: “Under & Over: A controlled study to develop an upper limb rehabilitation tool for people with Multiple Sclerosis.”  This study is now recruiting – find out more information on the...

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How healthy is your Brain?

As 2021 rapidly speeds up and COVID-19 leaves its trail of destruction it is clear to see how important general and brain health is for resilience against disease and its broader impact. These lessons go beyond COVID-19 and apply to any disease. This is why our #BrainHealth #TimeMatters campaign is so important for people with MS (pwMS) and the general public and why prehabilitation needs to...

MS Vaccine

The development of COVID-19 and the rapid way that RNA vaccines have been developed means that you have a rapid way of developing vaccines against your viruses of choice. So which virus do you want to get rid off…The ones that cause warts Hope this doesn’t put you off your rice crispies this morning:-) Epstein Barr Virus? Well ProfGs wish is their command, maybe he can convince them...

Grey Matter

I read this paper and it says Grey Matter is the thing to monitor and then we go at a trial and its whole brain atrophy. Why? Association of Gray Matter Atrophy Patterns with Clinical Phenotype and Progression in Multiple Sclerosis.Rocca MA, Valsasina P, Meani A, Gobbi C, Zecca C, Rovira A, Sastre-Garriga J, Kearney H, Ciccarelli O, Matthews L, Palace J, Gallo A, Bisecco A, Lukas C...

Sod the #MSCOVID19 vaccine give me the MS trials

You can have loads of ideas but you can’t do all the science on the planet, but it is nice to see an idea come true. Since the COVID-19 pandemic arrived Now what do I mean Sod the COVID vaccine, well of course I dont mean don’t take it if you are offered it. But what is the vaccine going to do? Hopefully, it is going to stop you getting symptomaic infected so that you do not pass on...

SDMT

Is the Symbol Digit Modalities Test a useful outcome in secondary progressive multiple sclerosis? Koch MW, Mostert J, Repovic P, Bowen JD, Uitdehaag B, Cutter G. Eur J Neurol. 2021 Jan 15. doi: 10.1111/ene.14732. Online ahead of print Background: It is unclear which cognitive outcome measure is the most useful for clinical trials in multiple sclerosis. To investigate the usefulness of the...

Central Vein for MS diagnosis

Mention veins and I geta shiver down my spine with the thought of CCSVI and blocked veins However, I heard about central veins from my ex-roomy ProfK. Ex…..cos I have been kicked out due to COVID-19, will I ever get back in? He told me about FLAIR* pronounced flare-snowflake, I mean flare-star. This is a combined magnetic resosoance contrast technique for visualizing White Matter Lesions...

Reflections on 2020 and a quick look forward to 2021

During my physical rehabilitation exercise session yesterday I realised that I have not reflected on the New Year from an MS or personal perspective be it MS research, MS clinical practice or my personal life. I suspect I have been distracted by my injuries and recovery and that the COVID-19 pandemic has pushed the New Year transition into the future. The political mayhem across the world has...

Monkey MS

A few years ago it was found that some monkeys in Portland, USA developed a demyelinating disease that looked abit like MS. The found out that it was caused by a herpes virus abit like EBV. Now they ask is there autoimmunity to myelin and the answer appears to be Yes. Myelin-specific T cells in animals with Japanese macaque encephalomyelitis.Govindan AN, Fitzpatrick KS, Manoharan M, Tagge I...

Cladribine switch

Sorry this post was launched before I had even written it. So the idea that memory B cells may be important is getting some traction with some people but for others they don’t care. However, if people start to study these ideas them information surfaces and you then have to ask is the idea wrong. In this study they say cladribine gets rid of memory B cells if it is working and them also say...

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