ArchiveSeptember 2011

Research: Stem cell breakthrough discovery for MS

You have again been searching the News again and there has been some debate amongst the bloggers, about a report from Cleveland Ohio, USA by Najm et al. Nature Methods 24 Sept. It is good that you Bloggers posts things and maybe we can have a new feature(Mouse)Doctoring the News! This is what this Blog is about unravelling the Research News..Bad or Good.. As you must realise we at Team G believe...

Team G News: Great North Run

Just to Let you Know that they Did It and Completed the Great North Run.A Big Thank You to all their sponsors who helped Team G and the Shift Speedies raise well over £2,500 for MS Charity.
Well Done to Beki, Tom, Adriana, Dr. Ruth, Sam and Surinder (Indian G) , who stepped into the Prof’s shoes when Prof G couldn’t make it.

Research & Bad Media:Yet another Cure Comming your way

A news story has been surfacing today “Daily pill to prevent or even cure multiple sclerosis in pipeline” They say “This is frankly an exciting breakthrough and has huge potential. The role of neurosteroids in the brain has been known for some time but no one thought, until now, that they might play a role in MS…When mice with MS were treated with the neurosteroid it cut...

Education: Treating Progressive MS-PostScript

We have been slowly building up a picture of how primary progressive MS may develop using transport analogies with cars and underground trains to ask “What is the problem in PPMS?”, “Why don’t Current MS drugs work in PPMS?” Now I reshow the first instalment and hope that it is not as complicated as some of you thought when if was first posted (Most thought it was...

Survey Results: Just because you can, Does it mean you should?

Well the results of the poll are in. Question: Do you want to know whether blood or plasma from young animals can stimulate faster remyelination in older animals using the parabiosis experiment? The majority of you who responded were in favour of performing the parabiosis experiment to determine whether something in young blood helped myelin repair. So with this positive result, you may be...

Education: Targeting Progressive MS-Part VIII

If you can’t remember the story so far see: Part I , Part II (Nerve Network), Part III (Nerve Plasticity), Part IV (Immune Attack), Part V (Slow Repair), Part VI (Response to Immune Therapy), Part VII (Progression) We have now built up the picture to understand the probable causes of progression we can see how it progresses and what we need for treatment.Nerves are stopping working as trains are...

Research: Just Because You Can, Does It Mean You Should?

You recently asked me a question: ” A question for the MouseDoctor, don’t you think sewing mice together is unethical?” This question was based on Prof G’s post about results from a Parabiosis, experiment. This is the surgical act of artificially creating conjoined twin (Siamese twins for the un-PC ones) of two organisms. These experiments often create animals that are living...

Education: Targeting Progressive MS-Part VII

If you can’t remember the story so far see: Part I , Part II (Nerve Network), Part III (Nerve Plasticity), Part IV (Immune Attack), Part V (Slow repair), Part VI (Response to Immune Therapy).We have now built up the picture to understand the probable causes of Progression. I say probable as this is still theory, I’m afraid to say. At each tube station (Node of Ranvier), people (ions) will...

Education: Targeting Progressive MS-Part VI

If you can’t remember the story so far see: Part I , Part II (theNerve Network), Part III (Nerve Plasticity), Part IV (Immune Attack), Part V (Slow Repair) Response to Immune Therapy. For many, many years the problem of MS whether it was primary, secondary progressive or relapsing-remitting disease was thought to be a problem of the immune system. Therefore, dealing with the white blood cell...

Team G News: Greath North Run

Just to Keep You up to Date with Activities of more Members in the Lab. Team G are running in the BUPA Great North Runon 18th September 2011 in Newcastle For those of you that don’t know that’s a half marathon (13.1miles or 21.1km) So Good Luck to Beki, Adriana, Prof G, Sam RB and Dr Ruth (Too busy Training to have photo done) If you can spot the odd one out (Clue: Names on T shirts)...

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