ArchiveSeptember 2011

Trends in MS disability progression at a population level

Epub ahead of print: Shirani et al. Temporal trends of disability progression in multiple sclerosis: findings from British Columbia, Canada (1975-2009). Mult Scler. 2011 Sep 27. Background: Recent natural history studies suggest that MS is a more slowly progressing disease than previously thought. These observations are from studies separated by time, geography and methodological...

How common do post-LP headaches occur in research subjects?

Epub ahead of print: de Almeida et al. Incidence of Post-Dural Puncture Headache in Research Volunteers. Headache. 2011 Jul 28. doi: 10.1111/j.1526-4610.2011.01959.x. Objective: To determine the frequency and risk factors of post-LP headache (PLPH) in research volunteers.  Background: Despite increasing interest in measuring cerebrospinal fluid (CSF) biomarkers to investigate...

Making EUReMS count for people with multiple sclerosis

The Lancet Neurology. Making EUReMS count for people with multiple sclerosis. Lancet Neurol. 2011 Oct;10(10):865. An insightful editorial on the new European Register for Multiple Sclerosis (EUReMS), which aims to collect comparable and reliable data on MS across the EU.  The mains points are: EUReMS was launched on July 1, 2011 The first forum to discuss the project will be held at the...

Where are the progressive MS’ers? Is there a lack of interest in slowing or stopping progressive MS?

The response to our call for progressive and other MS’ers to watch this video and complete the survey has been surprisingly poor (14 respondents so far). It makes me wonder about all the complaining progressive MS’ers do in relation to there being no treatments for progressive disease and the lack of research. Without a clear signal from you that you are prepared to have lumbar...

Research: Stem cell breakthrough discovery for MS

You have again been searching the News again and there has been some debate amongst the bloggers, about a report from Cleveland Ohio, USA by Najm et al. Nature Methods 24 Sept. It is good that you Bloggers posts things and maybe we can have a new feature(Mouse)Doctoring the News! This is what this Blog is about unravelling the Research News..Bad or Good.. As you must realise we at Team G believe...

Politics and Science: the stem cell wars

If you get a chance please read the ‘News in Focus’ piece in the 22nd Sept. Nature; ‘Texas prepares to fight for stem cells‘, by David Cyranoski. Some quotes from the article to wet your appetite: Paul Knoepfler: ‘Any procedure involving removing cells from the body and manipulating them — even if it’s something as simple as centrifuging them or putting...

High-field MRI expands the iceberg

Epub ahead of print: Bluestein et al. T1 and proton density at 7 T in patients with multiple sclerosis: an initial study. Magn Reson Imaging. 2011 Sep 19. MRI of cortical lesions (gray matter on the surface of the brain*)due to MS has been hampered by the lesions’ small size and low contrast to adjacent, normal-appearing tissue.  * the cortex of the brain is where...

Team G News: Great North Run

Just to Let you Know that they Did It and Completed the Great North Run.A Big Thank You to all their sponsors who helped Team G and the Shift Speedies raise well over £2,500 for MS Charity.
Well Done to Beki, Tom, Adriana, Dr. Ruth, Sam and Surinder (Indian G) , who stepped into the Prof’s shoes when Prof G couldn’t make it.

Research & Bad Media:Yet another Cure Comming your way

A news story has been surfacing today “Daily pill to prevent or even cure multiple sclerosis in pipeline” They say “This is frankly an exciting breakthrough and has huge potential. The role of neurosteroids in the brain has been known for some time but no one thought, until now, that they might play a role in MS…When mice with MS were treated with the neurosteroid it cut...

Spasticity and disability

Sosnoff et al. Influence of spasticity on mobility and balance in persons with multiple sclerosis. J Neurol Phys Ther. 2011 Sep;35(3):129-32. Background: Spasticity (stiffness of muscles) presumably affects mobility and balance. This study examined whether or not MS’ers with spasticity in their lower legs have more impairment of mobility and balance compared to those without...

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