The first People’s Hot Topic for Research.ms

T
Hello one and all,

Just thought I’d share Ram’s brilliant vid on Vitamin D. He answered questions put to us by MS’ers, about his specialist subject. Feel free to share with anyone you think might be interested.

Let me know if you have any feedback, ideas etc. And please do comment on the post if you wish!

http://shift.ms/magazine/ – The Magazine homepage

http://shift.ms/magazine/2011/09/vitamin-d-your-questions-answered/ – The article itself.

Enjoy!

Beki Aldam
Shift.ms Community Coordinator

About the author

Prof G

Professor of Neurology, Barts & The London. MS & Preventive Neurology thinker, blogger, runner, vegetable gardener, husband, father, cook and wine & food lover.

9 comments

  • Anonymous said…

    The problem is that all doctors arem't yet aware or convinced about Vit D. Neurologists need to know and also family physicians and others
    Thursday, September 22, 2011 2:00:00 AM

  • Interesting, but then I looked at the research area of shift.ms and there is an article saying that vit D may give short term relief from inflammation but long term will exacerbate symptoms (from Autoimmunity Reviews 16.4.09). What are we supposed to believe?

  • "Interesting, but then I looked at…"

    Hi Anonymous,
    I can't seem to find the page you are referring to on shift.ms

    I think the article you are referring to is this one
    http://www.sciencedirect.com/science/article/pii/S1568997209000457

    This article is what is called a review and this one is a highly speculative one. While everyone is obviously entitled to their own opinions there is no evidence whatsoever to suggest that vitamin D exacerbates MS.

    A number of actual research studies have highlighted that vitamin D deficiency correlates with risk of relapse e.g.

    http://www.ncbi.nlm.nih.gov/pubmed/20437559
    http://www.ncbi.nlm.nih.gov/pubmed/20695012
    http://www.ncbi.nlm.nih.gov/pubmed/19321461

    Furthermore, safety studies of giving high dose vitamin D to MS'ers have shown it to be safe (and likely protective):

    http://www.ncbi.nlm.nih.gov/pubmed/20427749

    The gold standard of evidence for us researchers is a randomised controlled trial. The SOLAR trial (http://www.ncbi.nlm.nih.gov/pubmed/21620416) is currently addressing whether or not high dose vitamin D as a treatment prevents relapses as compared to a non-treated group-
    we should get the results from this trial soon.

    This gold standard of evidence is available for fracture prevention
    http://www.ncbi.nlm.nih.gov/pubmed/15886381, which as mentioned before is a problem for MS'ers.

    Team G strongly believe that is important for MS'ers to ensure that they are vitamin D replete!

  • Somehow I got a link to the MS Trust and it was an article by Albert PJ, et al- Vitamin D: The Alternative Hypothesis.

    I agree about Vit D anyway. All the high dose Vit D seem to be in the form of gel capsules. Do they pose any problem for those treated with alemtuzumab in their 3 month 'watch out what you eat phase'?

  • Re: "Team G these videos are really interesting and useful! Leave the veg to Delia and do more of these please!"

    The veg was an art project that was created to expose the MS naïve and children about the disease in a way they could relate to. We simply helped Alison Thompson with her material. Those pieces were not created for this blog. Please judge them in context. I think they are great and Alison should be encouraged to continue to expand awareness of MS using her skills. Our mistake was not to put them into the correct context before we launched them to the world.

  • Re: "I agree about Vit D anyway. All the high dose Vit D seem to be in the form of gel capsules. Do they pose any problem for those treated with alemtuzumab in their 3 month 'watch out what you eat phase'?"

    No at all. Think of them as 20 to 30 minutes of sunshine in a capsule. There is a small risk that they may raise calcium levels in people who are predisposed to this condition or take calcium supplements. If in doubt ask your neurologist or GP.

By Prof G

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