ArchiveDecember 2011

research: sleep

Kaminska M et al. Obstructive sleep apnea is associated with fatigue in multiple sclerosis.Mult Scler. 2011 Dec 19. [Epub ahead of print] Background: Multiple sclerosis (MS) patients often suffer from fatigue. Objective: We evaluated the relationship of obstructive sleep apnea to fatigue and sleepiness in MS patients.Methods: Ambulatory MS patients without known sleep disorders and healthy...

MS life 2012

MS Life (UK MS Society meeting) will be heading to Manchester Central for 14-15 April 2012. Make it a Date for Your Diary
Come and See Familiar & New Faces and the Science Trilogy From Holland
Meet the Scientists and Members of Team G. Hopefully the T shirts won’t be such a tight fit.

Don’t forget to Register

Cost of Neurological Disease in Europe

Olesen J et al. The economic cost of brain disorders in Europe.Eur J Neurol. 2012 Jan;19(1):155-162. Background and purpose:  In 2005, we presented for the first time overall estimates of annual costs for brain disorders (mental and neurologic disorders) in Europe. This new report presents updated, more accurate, and comprehensive 2010 estimates for 30 European countries. Methods:  One-year...

Research: Fingolimod in Volunteers

Epub: Boulton C et al. Pharmacodynamic Effects of Steady-State Fingolimod on Antibody Response in Healthy Volunteers: A 4-Week, Randomized, Placebo-Controlled, Parallel-Group, Multiple-Dose Study. J Clin. Pharmacol 2011 Dec. Fingolimod (Gilenya) , a first-in-class oral sphingosine 1-phosphate receptor (S1PR) modulator, is approved in many countries for relapsing-remitting multiple sclerosis, at a...

Planning MS: It just takes a little longer

Denney DR et al. Deficits in Planning Time but not Performance in Patients with Multiple Sclerosis.Arch Clin Neuropsychol 2011 Dec 15. [Epub ahead of print] Studies of planning ability typically involve some version of the Tower of Hanoi or Tower of London tests. When these tests are administered to patients with multiple sclerosis (MS), the findings pertaining to planning...

Research: Spinal Lesions at First neurological signs increase risk of MS

Patrucco L, Rojas JI, Cristiano E Assessing the value of spinal cord lesions in predicting development of multiple sclerosis in patients with clinically isolated syndromes.J Neurol. 2011 Dec [Epub ahead of print] The purpose of this study was to determine the value of spinal cord lesions as a predictive factor for conversion in clinically isolated syndrome (CIS) patients. Patients with CIS and...

Research: Predicting MS from Genes

Jafari N et al. Perspectives on the Use of Multiple Sclerosis Risk Genes for Prediction. Plos One 2011;6(12):e26493. OBJECTIVE: A recent collaborative genome-wide association study replicated a large number of susceptibility loci and identified novel loci. This increase in known multiple sclerosis (MS) risk genes raises questions about clinical applicability of genotyping. In an empirical set we...

Happy Holiday

What Every Your Religion,Whether it be: Atheist, Agnostic, Christian, Jewish, Muslim, Hindu or CCSVI and Others
Prof G, the MouseDoc & Team G Wish You Happy Holidays. Hoping SantaMouse Delivers Effective Treatments to You

Research:EBV activating the Immune Response

Tzartos JS, Khan G, Vossenkamper A, Cruz-Sadaba M, Lonardi S, Sefia E, Meager A, Elia A, Middeldorp JM, Clemens M, Farrell PJ, Giovannoni G, Meier UC. Association of innate immune activation with latent Epstein-Barr virus in active MS lesions.Neurology 2011 Dec [Epub] OBJECTIVE: To determine whether the activation of innate immune responses, which can be elicited by pathogenic and endogenous...

24 MS Research Day Advent Calendar

Please remember to register your interests for the Open Day, You can do this if you Click Here.NativityMice say come to our Research Day and… Meet and Talk to Members of Team G Hear the Trials & Tribulations of MS Drugs 2012? Review Stem Cells Trials for 2012 and Beyond Talk the walk about symptomatic therapy Speak to Prof G and the Other Neuros See who the MouseDoctors Really Are Hear...



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