ArchiveDecember 2011

research: sleep

Kaminska M et al. Obstructive sleep apnea is associated with fatigue in multiple sclerosis.Mult Scler. 2011 Dec 19. [Epub ahead of print] Background: Multiple sclerosis (MS) patients often suffer from fatigue. Objective: We evaluated the relationship of obstructive sleep apnea to fatigue and sleepiness in MS patients.Methods: Ambulatory MS patients without known sleep disorders and healthy...

MS life 2012

MS Life (UK MS Society meeting) will be heading to Manchester Central for 14-15 April 2012. Make it a Date for Your Diary
Come and See Familiar & New Faces and the Science Trilogy From Holland
Meet the Scientists and Members of Team G. Hopefully the T shirts won’t be such a tight fit.

Don’t forget to Register

Cost of Neurological Disease in Europe

Olesen J et al. The economic cost of brain disorders in Europe.Eur J Neurol. 2012 Jan;19(1):155-162. Background and purpose:  In 2005, we presented for the first time overall estimates of annual costs for brain disorders (mental and neurologic disorders) in Europe. This new report presents updated, more accurate, and comprehensive 2010 estimates for 30 European countries. Methods:  One-year...

Long-acting interferon beta

Epub ahead of print:  Kieseier  & Calabresi. PEGylation of Interferon-β-1a: A Promising Strategy in Multiple Sclerosis. CNS Drugs. 2011 Dec 23. Biological therapies, such as interferon beta, can be hindered by the rapid clearance of the drug requiring frequent dosing. One strategy for addressing this problem is drug modification through PEGylation, a well established...

Research: Fingolimod in Volunteers

Epub: Boulton C et al. Pharmacodynamic Effects of Steady-State Fingolimod on Antibody Response in Healthy Volunteers: A 4-Week, Randomized, Placebo-Controlled, Parallel-Group, Multiple-Dose Study. J Clin. Pharmacol 2011 Dec. Fingolimod (Gilenya) , a first-in-class oral sphingosine 1-phosphate receptor (S1PR) modulator, is approved in many countries for relapsing-remitting multiple sclerosis, at a...

Planning MS: It just takes a little longer

Denney DR et al. Deficits in Planning Time but not Performance in Patients with Multiple Sclerosis.Arch Clin Neuropsychol 2011 Dec 15. [Epub ahead of print] Studies of planning ability typically involve some version of the Tower of Hanoi or Tower of London tests. When these tests are administered to patients with multiple sclerosis (MS), the findings pertaining to planning...

Kick-Boxing

Jackson et al. Feasibility and effects of a group kickboxing program for individuals with multiple sclerosis: A pilot report. J Bodyw Mov Ther. 2012 Jan;16(1):7-13. BACKGROUND AND PURPOSE: Balance and mobility impairments are common in MS’ers. The primary purpose of this pilot program was to evaluate the feasibility and the effects of group kickboxing on balance and mobility...

Cognitive testing for all

Epub ahead of print:  Langdon et al. Recommendations for a Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS). Mult Scler. 2011 Dec 21.  Background: Cognitive impairment in MS impacts negatively on many MS’ers at all disease stages and in all subtypes. Full clinical cognitive assessment is expensive, requiring expert staff and special equipment...

Research: Spinal Lesions at First neurological signs increase risk of MS

Patrucco L, Rojas JI, Cristiano E Assessing the value of spinal cord lesions in predicting development of multiple sclerosis in patients with clinically isolated syndromes.J Neurol. 2011 Dec [Epub ahead of print] The purpose of this study was to determine the value of spinal cord lesions as a predictive factor for conversion in clinically isolated syndrome (CIS) patients. Patients with CIS and...

Research: Predicting MS from Genes

Jafari N et al. Perspectives on the Use of Multiple Sclerosis Risk Genes for Prediction. Plos One 2011;6(12):e26493. OBJECTIVE: A recent collaborative genome-wide association study replicated a large number of susceptibility loci and identified novel loci. This increase in known multiple sclerosis (MS) risk genes raises questions about clinical applicability of genotyping. In an empirical set we...

Translate

Categories

Recent Posts

Recent Comments

Archives