ArchiveFebruary 2012

Causes of death in MS

Epub ahead of print: Lalmohamed et al. Causes of death in patients with multiple sclerosis and matched referent subjects: a population-based cohort study. Eur J Neurol. 2012 Feb 21. doi: 10.1111/j.1468-1331.2012.03668.x.  Background and purpose:  MS is associated with increased mortality rates. However, influence of lifestyle parameters remains unknown, and inconsistencies...

Mesenchymal stem cells in autoimmune neuritis

Sajic et al. Mesenchymal Stem Cells Lack Efficacy in the Treatment of Experimental Autoimmune Neuritis despite In Vitro Inhibition of T-Cell Proliferation. PLoS One. 2012;7(2):e30708. Epub 2012 Feb 16. Mesenchymal stem cells have been demonstrated to ameliorate experimental autoimmune encephalomyelitis (EAE), a model of MS, prompting clinical trials in MS which are currently ongoing. An important...

New survey: MS Heroes

Do you think we should celebrate MS heroes (MS’ers who are special) on this blog? If you are using a mobile blogger to view this post or email alerts please log-on via the web to complete the poll.  “This survey may yet prove to be contentious, but heroes often make us see the world differently. Seeing things differently is something we have to do if we have MS or are close to...

Survey results: Facebook

“I am not surprised by this result considering how many of the world’s population now socialise within Facebook. Our problem is simply time. We already spend a large number of hour per week running the blog and don’t have the resource to run a Facebook page as well. Maybe this is an opportunity for us to get some of you involved to help keep the blog, twitter...

Cognitive impairment and motor dysfunction are associated with each other in MS

Epub ahead of print:  D’Orio et al. Cognitive and motor functioning in patients with multiple sclerosis: Neuropsychological predictors of walking speed and falls. J Neurol Sci. 2012 Feb 20.   While motor (power and coordination) and cognitive impairments (memory, calculations, time-keeping, problem solving) are common in MS’ers, research concerning their...

Fingolimod in Japanese MS’ers

Epub ahead of print:  Saida et al. A randomized, controlled trial of fingolimod (FTY720) in Japanese patients with multiple sclerosis. Mult Scler. 2012 Feb 21.  Background: Fingolimod (FTY720) has previously shown clinical efficacy in phase II/III studies of predominantly Caucasian populations with MS. Objectives: To report 6-month efficacy and safety outcomes in Japanese...

Pediatric MS in The Netherlands

Epub ahead of print: Ketelslegers et al. Incidence of acquired demyelinating syndromes of the CNS in Dutch children: a nationwide study. J Neurol. 2012 Feb 17. Acquired demyelinating syndromes (ADS) can be a first presentation of MS in children. The incidence of these disorders in Europe is currently unknown. Children (<18 years old) living in the Netherlands who presented with ADS were...

Motor fatigue in MS: transcranial magnetic stimulation

Epub ahead of print:  Scheidegger et al. Corticospinal output during muscular fatigue differs in multiple sclerosis patients compared to healthy controls. Mult Scler. 2012 Feb 21.  Background: In MS, fatigue is a common and often a disabling symptom. Fatigue has multiple causes with central motor fatigue playing an important role. Objective: The objective of this study was to...

Plagiarism in MS Research (1): cognitive deficits in MS

Epub ahead of print:  Caramia F, Tinelli E, Francia A, Pozzilli C. Retraction Note: Cognitive deficits in multiple sclerosis: a review of functional MRI studies. Neurol Sci. 2012 Feb 15. Source: Department of Neurological Sciences, University of Rome, ”La Sapienza”, Viale dell’Università 30, 00185, Rome, Italy, francesca.caramia@uniroma1.it. Retraction Note:...

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