ArchiveAugust 2012

Team G News: Leaving us


Bye Bye Beki from Shift MS, who is moving on to pastures new.

Nurse Maria Espasandin Research Manager has also jumped Ship to work with the Enemy (🙂) ..Oops sorry Pharma. 

Missing You Already

We wish them well in their New Jobs

Research: Mixing statins with Interferons do not add up

Bhardwaj S, Coleman CI, Sobieraj DM.Efficacy of statins in combination with interferon therapy in multiple sclerosis: A meta-analysis. Am J Health Syst Pharm. 2012;69:1494-9. PURPOSE: The efficacy of statins in combination with interferon therapy in patients with multiple sclerosis (MS) is reviewed. METHODS: A systematic literature search was conducted through September 2011 to identify...

Research: Clinical Improvement after Venoplasty of CCSVI.

Epub: Hubbard D et al. Clinical Improvement after Extracranial Venoplasty in Multiple Sclerosis. Journal of Vascular and Interventional Radiology Epub online 28 August 2012.  Purpose: This study proposed to prospectively evaluate safety and clinical changes in outpatient endovascular treatment in patients with multiple sclerosis (MS) and chronic cerebrospinal venous insufficiency...

Unrelated Blogger Comments August

Sometimes you want to say something that is unrelated to the threads. This is a spot for you . “If you are a MSer at the Royal London Hospital please sign-up for our cognition study!” We may be slow at answering this Month  35 comments: AnonymousFriday, August 17, 2012 2:23:00 PM Alemtuzumab will no longer be sold in the UK I guess it will return at a much higher price when...

Research: Further evidence that Neurofilaments are a useful biomarker to detect damage

Khalil M et al. CSF neurofilament and N-acetylaspartate related brain changes in clinically isolated syndrome. Mult Scler. 2012 Aug. [Epub ahead of print] BACKGROUND: Axonal damage is considered a major cause of disability in multiple sclerosis (MS) and may start early in the disease. Specific biomarkers for this process are of great interest.  OBJECTIVE: To study if cerebrospinal fluid...

Research: sativex can alleviate spasticity in mice

Hilliard A, Stott C, Wright S, Guy G, Pryce G, Al-Izki S, Bolton C, Giovannoni G. Evaluation of the Effects of Sativex (THC BDS: CBD BDS) on Inhibition of Spasticity in a Chronic Relapsing Experimental Allergic Autoimmune Encephalomyelitis: A Model of Multiple Sclerosis. ISRN Neurol. 2012;2012:802649. Epub 2012 Aug 7. This study investigated the anti-spasticity potential of Sativex in mice...


The 14th paralympics start in London today and this week many people will see wheelchair users (and blade runners, blind, deaf and walking enabled etc.) in a whole new light.


Best of Luck to Everyone

Research: Anyone for Green Tea. A Crucial Brew?

Herges K, Millward JM, Hentschel N, Infante-Duarte C, Aktas O, et al. (2011) Neuroprotective Effect of Combination Therapy of Glatiramer Acetate and Epigallocatechin-3-Gallate in Neuroinflammation. PLoS ONE 6(10): e25456. doi:10.1371/ journal.pone.0025456 Multiple sclerosis (MS) is an inflammatory autoimmune disease of the central nervous system. However, studies of MS and the animal model...

Oligoclonal bands in MSers: worse prognosis?

Epub: Rojas et al. Oligoclonal bands in multiple sclerosis patients: worse prognosis? Neurol Res. 2012 Aug. INTRODUCTION: Cerebrospinal fluid (CSF) oligoclonal bands (OB) imply intrathecal immunoglobulin synthesis and B-cell immune process. There is scarce evidence of OB having a role in disease prognosis. The objective of the present study was to determine OBs prognostic value regarding...

Research: Interleukin -7 a risk factor is reduced in MS

Kreft KL, Verbraak E, Wierenga-Wolf AF, van Meurs M, Oostra BA, Laman JD, Hintzen RQ. Decreased systemic IL-7 and soluble IL-7Rα in multiple sclerosis patients.Genes Immun. 2012 Aug 23. doi: 10.1038/gene.2012.34. [Epub ahead of print]. Polymorphisms (single-nucleotide polymorphism (SNP)) in the interleukin-7 receptor-α (IL-7Rα)/IL-7 pathway are associated with an increased risk to develop...



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