ArchiveJanuary 2013

Research: excerise and MS

Asano et ak. Exercise barriers and preferences among women and men with multiple sclerosis. Disabil Rehabil. 2013 Mar;35(5):353-61. doi: 10.3109/09638288.2012.742574. Purpose: The primary objective of this study was to estimate the extent to which women and men with MS present different exercise barriers. The secondary objective was to estimate the extent to which women and men with MS present...

CCSVI Research: Now Pigs! Should we save them for bacon?

Epub: Habib et al. MR imaging of the yucatan pig head and neck vasculature. J Magn Reson Imaging. 2013 Jan 24. doi: 10.1002/jmri.24003.  PURPOSE: To evaluate the cerebral venous drainage system of the swine as a probable model to test whether extracranial venous abnormalities may play a role in neurodegenerative diseases as reported recently in multiple sclerosis. MATERIALS AND METHODS:...

Are you an Ostrich?

We have invented some fun terms on the blog like a Shania.  Today we have the “Ostrich”. This is someone, who is stuck in the world of Dogma. They just stick their head in the ground and ignore the real world. Science is full of Ostriches, and they talk to a mirror everyday to say how great they…….eventually they believe themselves. They ostrich convinces...

Research Early MS lesion not around Blood Vessels

Singh S, Metz I, Amor S, van der Valk P, Stadelmann C, Brück W. Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons. Acta Neuropathol. 2013 Jan 26. [Epub ahead of print] Microglial nodules in the normal-appearing white matter have been suggested as the earliest stage(s) of multiple sclerosis (MS) lesion formation. Such nodules are characterized by an...

Research: Tracking MS

Epub: Neven et al. Documenting outdoor activity and travel behaviour in persons with neurological conditions using travel diaries and GPS tracking technology: a pilot study in multiple sclerosis. Disabil Rehabil. 2013 Jan. Objective: Persons with multiple sclerosis (PwMS) experience several physical and cognitive problems which can influence their travel behaviour. This study aimed to...

How will the CosMo study on CCSVI work

Comi G, Battaglia MA, Bertolotto A, Del Sette M, Ghezzi A, Malferrari G, Salvetti M, Sormani MP, Tesio L, Stolz E, Mancardi G. Italian multicentre observational study of the prevalence of CCSVI in multiple sclerosis (CoSMo study): rationale, design, and methodology. Neurol Sci. 2013 Jan. [Epub ahead of print]   Chronic cerebro-spinal venous insufficiency (CCSVI) has been proposed as a...

Alternative Medicine..safe? But where is the Evidence?

Senders et al. Mind-body medicine for multiple sclerosis: a systematic review. Autoimmune Dis. 2012;2012:567324. doi: 10.1155/2012/567324. Background: Mind-body therapies are used to manage physical and psychological symptoms in many chronic health conditions. Objective: To assess the published evidence for using mind-body techniques for symptom management of multiple sclerosis. Methods. MEDLINE...

Imaging the blood brain barrier

Coisne C, Lyck R, Engelhardt B Live cell imaging techniques to study T cell trafficking across the blood-brain barrier in vitro and in vivo Fluids Barriers CNS. 2013 ;10(1):7. [Epub ahead of print]   BACKGROUND: The central nervous system (CNS) is an immunologically privileged site to which access for circulating immune cells is tightly controlled by the endothelial blood–brain barrier...

Research: MCAM a marker of inflammation

Epub: Duan et al. Soluble CD146 in cerebrospinal fluid of active multiple sclerosis.Neuroscience. 2013 Jan  doi:pii: S0306-4522(13)00050-X. 10.1016/j.neuroscience.2013.01.020.  Background: The soluble form of CD146 has been reported to be present in various inflammatory diseases and displays pro-inflammatory properties. However, little is known about sCD146 in multiple sclerosis...

CCSVI monthly January

Epub: Carraro et al. Optic Nerve and its Arterial-Venous Vascularization: An Ultrasonologic Study in Multiple SclerosisPatients and Healthy Controls.J Neuroimaging. 2012 Dec. doi: 10.1111/j.1552-6569.2012.00758.x. BACKGROUND: Recent studies suggest that alterations in the cerebrospinal venous system may play a role in multiple sclerosis (MS) and that chronic cerebrospinal venous insufficiency...

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