ArchiveJanuary 2013

Research: excerise and MS

Asano et ak. Exercise barriers and preferences among women and men with multiple sclerosis. Disabil Rehabil. 2013 Mar;35(5):353-61. doi: 10.3109/09638288.2012.742574. Purpose: The primary objective of this study was to estimate the extent to which women and men with MS present different exercise barriers. The secondary objective was to estimate the extent to which women and men with MS present...

Brain atrophy: what to do about it?

#MSBlog: Should we be measuring brain atrophy in routine clinical practice? “I was asked by a colleague in Porto last week whether or not I let the presence or absence of brain atrophy on MRI affect my clinical decision making about DMTs and treatment? I had to think about the question and haven’t stopped thinking about it since. The first problem is that our neuroradiologists...

CCSVI Research: Now Pigs! Should we save them for bacon?

Epub: Habib et al. MR imaging of the yucatan pig head and neck vasculature. J Magn Reson Imaging. 2013 Jan 24. doi: 10.1002/jmri.24003.  PURPOSE: To evaluate the cerebral venous drainage system of the swine as a probable model to test whether extracranial venous abnormalities may play a role in neurodegenerative diseases as reported recently in multiple sclerosis. MATERIALS AND METHODS:...

CCSVI treatment: no major effect

#MSBlog: Venoplasty for CCSVI appears not to work! Do we need more data? Epub: Ghezzi et al; The MS Study Group-Italian Society of Neurology. Endovascular treatment of CCSVI in patients with multiple sclerosis: clinical outcome of 462 cases. Neurol Sci. 2013 Jan 25. Background: Although it is still debated whether chronic cerebro-spinal venous insufficiency (CCSVI) plays a role in MS development...

4th MS Research Day – 2nd Febuary 2013

If you can’t make the research day on Saturday you can follow the event on Twitter. We will be using the following hashtag(#): #msresearchday. For those of you new to Twitter: YOU CANNOT “FOLLOW” A HASHTAG DIRECTLY THROUGH YOUR TWITTER ACCOUNT. This is generally a confusing point for those of you who are new to Twitter and hashtags (#). A hashtag is not a source of tweets; it...

Are you an Ostrich?

We have invented some fun terms on the blog like a Shania.  Today we have the “Ostrich”. This is someone, who is stuck in the world of Dogma. They just stick their head in the ground and ignore the real world. Science is full of Ostriches, and they talk to a mirror everyday to say how great they…….eventually they believe themselves. They ostrich convinces...

Research Early MS lesion not around Blood Vessels

Singh S, Metz I, Amor S, van der Valk P, Stadelmann C, Brück W. Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons. Acta Neuropathol. 2013 Jan 26. [Epub ahead of print] Microglial nodules in the normal-appearing white matter have been suggested as the earliest stage(s) of multiple sclerosis (MS) lesion formation. Such nodules are characterized by an...

Brain lesions in childhood MS are same as in adult onset MS

#MSBlog: Childhood and adult MS looks the same on MRI. Are you surprised?  Donohue et al. No Regional Gray Matter Atrophy Differences between Pediatric- and Adult-Onset Relapsing-Remitting Multiple Sclerosis.J Neuroimaging. 2013. doi: 10.1111/j.1552-6569.2012.00775.x.  OBJECTIVE: To investigate differences in region-specific gray matter (GM) damage between adults with pediatric-onset...

Research: Tracking MS

Epub: Neven et al. Documenting outdoor activity and travel behaviour in persons with neurological conditions using travel diaries and GPS tracking technology: a pilot study in multiple sclerosis. Disabil Rehabil. 2013 Jan. Objective: Persons with multiple sclerosis (PwMS) experience several physical and cognitive problems which can influence their travel behaviour. This study aimed to...

How will the CosMo study on CCSVI work

Comi G, Battaglia MA, Bertolotto A, Del Sette M, Ghezzi A, Malferrari G, Salvetti M, Sormani MP, Tesio L, Stolz E, Mancardi G. Italian multicentre observational study of the prevalence of CCSVI in multiple sclerosis (CoSMo study): rationale, design, and methodology. Neurol Sci. 2013 Jan. [Epub ahead of print]   Chronic cerebro-spinal venous insufficiency (CCSVI) has been proposed as a...

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