Foroughipour et al. Frequency of obsessive-compulsive disorder in patients with multiple sclerosis: A cross-sectional study. J Res Med Sci. 2012;17:248-53.
BACKGROUND: Obsessive compulsive disorder has been reported in MSers. Obsessive compulsive disorder (OCD) is a kind of anxiety disorder characterized by a combination of repetitive thoughts and repetitive behaviors for reducing anxiety.
MATERIALS AND METHODS: 112 MSers participated in this study. Demographic data were obtained through using their medical records. MS clinical subtypes, the duration of disease and neurological signs were determined. The Kurtzke Expanded Disability Status Scale (EDSS) was used to quantify disability in MS. OCD was confirmed by psychiatrist through using DSM-IV criteria. The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) was used to rate the severity of OCD. Data analysis was performed by SPSS for Windows software (version 15.0) and Chi-square test and Exact test were used for analyzing data.
RESULTS: The frequency of OCD in MSers was 16.1%. The OCD was significantly correlated with a higher EDSS score (X(2) = 86.515, P = 0.0001). OCD was also significantly correlated with the duration of disease, phenotypic subgroup, cranial nerve involvement, cerebellar, autonomic, sensory and motor nerve involvement.
CONCLUSIONS: OCD might be considered in quantifying disability of patients with MS. It might be suggested that all the patients with MS to be screened for OCD.
“This study’s results are surprising to me; an unexpected result that needs to be confirmed. I have a few MSers who have OCD, but I thought it was rare. This study suggests that as MS progresses Msers have a greater chance of developing OCD; i.e. the presence of OCD was associated with disease duration and some disabilities. Could OCD be another hidden psychiatric symptom? OCD can be very disabling so clearly would need to be looked for and treated. If you have OCD I would appreciate your thoughts.”
“If you are interested in finding out if you have OCD you can do a quick online questionnaire.”