ArchiveMay 2013

DMF or BG12 launch in US defies analysts predictions

Matthew Herper. Biogen Idec’s MS Drug Launch Is Going Amazingly Well. These Two Graphs Prove It. PHARMA & HEALTHCARE . 5/29/2013 @ 11:16AM  Sales of the dimethyl fumarate (Tecfidera) are destroying what were already very high expectations. Mark Schoenebaum at International Strategy & Investment Group noted on Tuesday that according to data from IMS Health...

Osteopontin a marker of MS activity

Szalardy L, Zadori D, Simu M, Bencsik K, Vecsei L, Klivenyi P. Evaluating biomarkers of neuronal degeneration and neuroinflammation in CSF of patients with multiple sclerosis-osteopontin as a potential marker of clinical severity. J Neurol Sci. 2013 May 21. doi:pii: S0022-510X(13)00204-9. 10.1016/ j.jns.2013.04.024. [Epub ahead of print] Biomarkers capable of predicting the clinical course and...

MS Medical Education in Istanbul

Multiple Sclerosis Continuing Medical Education comes to Istanbul. Interested in seeing the Programme? #MSBlog “I am in Istanbul at the 2013 CME Annual meeting in MS: How to translate new insights in MS into clinical practice. I have a very difficult talk to give on day 2 of the meeting; I am not sure what to speak about. I leaning towards MS Prevention.” “Istanbul is one city...

Brain damage and motor and cognitive function in MS

MRI is the window in the MSer brain; it is surprising how much damage MS causes. #MSBlog #MSResearch Sbardella et al. Assessing the Correlation between Grey and White Matter Damage with Motor and Cognitive Impairment in Multiple Sclerosis Patients.PLoS One. 2013 May 16;8(5):e63250. BACKGROUND: MS is characterized by demyelinating and degenerative processes within the central nervous system...

Pilatates and Aquatic Exercise aids balance

Marandi SM, Nejad VS, Shanazari Z, Zolaktaf V. A Comparison of 12 Weeks of Pilates and Aquatic Training on the Dynamic Balance of Women with Mulitple Sclerosis. Int J Prev Med. 2013 Apr;4(Suppl 1):S110-S117. BACKGROUND: Multiple Sclerosis (MS) is a disabling chronic disease of the nervous system in which the myelin system of the central nervous system is deteriorated. The objective of this...

Fatigue treatment trial

Believe it or not MS-related  can be treated with behavioural therapies. #MSBlog #MSResearch Epub: Thomas et al. A pragmatic parallel arm multi-centre randomised controlled trial to assess the effectiveness and cost-effectiveness of a group-based fatigue management programme (FACETS) for people with multiple sclerosis.J Neurol Neurosurg Psychiatry. 2013 May 22. BACKGROUND: Fatigue is a...

ISPOR 18th Annual International Meeting: BG12 and steroid usage

BG12 reduces the severity of relapses. #MSBlog #MSResearch “My poster from the ISPOR 18th Annual International Meeting in New Orleans. The main finding is that BG12 or DMF reduces the proportion of relapses needing to be treated with intravenous steroids. Use of steroids is a surrogate for the severity of relapses; in other words BG12 not only reduces the number of relapse, but also the...

Removing damaging immune responses from the brain saves nerves

Epub: Axelsson et al. Immunosuppressive therapy reduces axonal damage in progressive multiple sclerosis.Mult Scler. 2013 May 23.  BACKGROUND:In progressive multiple sclerosis (PMS), disease-modifying therapies have not been shown to reduce disability progression. OBJECTIVE:The impact from immunosuppressive therapy in PMS was explored by analyzing cerebrospinal fluid (CSF) biomarkers of...

Retinal ganglion cell loss in CIS

Early loss of retinal ganglion cells in CIS; is due to focal inflammation or diffuse neurodegeneration? #MSBlog #MSResearch Epub: Oberwahrenbrock et al. Retinal ganglion cell and inner plexiform layer thinning in clinically isolated syndrome. Mult Scler. 2013 May 23. BACKGROUND: Axonal and neuronal damage are widely accepted as key events in the disease course of MS. However...

Female sexual dysfunction

Are you a woman MSer with sexual dysfunction and being ignored? This post is for you. #MSBlog #MSResearch Lew-Starowicz & Rola. Prevalence of Sexual Dysfunctions Among Women with Multiple Sclerosis. Sex Disabil. 2013 Jun;31(2):141-153. Background: Sexual concerns are known to be common in women MSers but definite data on the prevalence of particular sexual dysfunctions (SD) remain...

Translate

Categories

Recent Posts

Recent Comments

Archives