A salty taste

van der Meer JW, Netea MG. A Salty Taste to Autoimmunity. N Engl J Med. 2013 Jun; 368:2520-2521.

This reports relates to the studies in Nature suggesting that high salt diet causes autoimmunity.

MD2 says 

“A salty taste……more like a fishy smell”

Maybe Ram can do an epidemeology study of the incidence of MS (autoimmunity) in regions with high salt diets. I can guess the answer.

The mean estimated salt intake, derived from urinary sodium excretion, for adults aged 19 to 64 years was 8.1g per day. Men had a mean estimated intake of 9.3g per day, and women had a mean estimated intake of 6.8g per day. 

Overall, 70% of participants had a daily intake of salt higher than the recommendation of no more than 6g per day. 80% of men and 58% of women exceeded this recommendation

An analysis of trends in salt intake (g per day), including all urinary sodium surveys carried out in UK countries between 2000/01 and 2011, showed a significant downwards trend in mean salt intake overall and also for both men and women separately.

Statistical analysis showed there has been a significant reduction in mean salt intake between 2000/01 and 2011 from 9.5g to 8.1g per day

But MS is on the way up in women…Go figure.

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  • This relates to the equally fishy study in mice as mentioned above. I did some back of an envelope calculations and deduce for the typical amount of food and water a mouse consumes a day and the salt content used in the experiment for this to be extrapolated to a 70 kg human you would need to consume half a kilo of salt per day! Indicating that you would be long dead well before you developed MS! As MD says, salt consumption is actually going down yet MS is on the increase, particularly in women.
    Link not proven.

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