ArchiveSeptember 2013

Time to Improve Standards in Animal Use

Today Universities were asked by the National Centre of Refinement, Reduction and Replacement of Animals in Research to pull their finger out and encourage their employers to perform and importantly report animal studies in a more rigorous fashion. This is a movement that is coming, if not in its present format in another guise, so better to embrace now than face rejection later on The failing in...

Stressed oligos activate microglia

Bsibsi M, Holtman IR, Gerritsen WH, Eggen BJ, Boddeke E, van der Valk P, van Noort JM, Amor S.Alpha-B-Crystallin Induces an Immune-Regulatory and Anti-viral Microglial Response in PreactiveMultiple Sclerosis Lesions. J Neuropathol Exp Neurol. 2013 Sep 13. [Epub ahead of print]Microglial nodules are frequently observed in the normal-appearing white matter of multiple sclerosis (MS) patients...

ECTRIMS Question Time

Our final member of the ECTRIMS Question time panel is the Chair and Head of Research at the National Multiple sclerosis Society Tim Coeztee

Remember to get a twitter account to tweak #MSQT

Cladribine works in rodents Should it?

Musella A, Mandolesi G, Gentile A, Rossi S, Studer V, Motta C, Sepman H, Fresegna D, Haji N, Paolillo A, Matarese G, Centonze D. Cladribine interferes with IL-1β synaptic effects in experimental multiple sclerosis. J Neuroimmunol. 2013 Aug. doi:pii: S0165-5728(13)00230-0. 10.1016/j.jneuroim.2013.08.009. [Epub ahead of print] Alterations of glutamate-mediated synaptic transmission occur in both...

ECTRIMS 2013

Twitter Feed for the Live event this week #MSQT

 Social Media Session 12.30-14.00 
(UK Time 11.30-13.00
Question Time.13.00-14.00
Pop-up window will be on the ECTRIMS website
we will post Link

Eye thinning an outcome for MS studies

Winges KM, Werner JS, Harvey DJ, Cello KE, Durbin MK, Balcer LJ, Calabresi PA, Keltner JL.Baseline Retinal Nerve Fiber Layer Thickness and Macular Volume Quantified by OCT in the North American Phase 3 Fingolimod Trial for Relapsing-Remitting Multiple Sclerosis.J Neuroophthalmol. 2013 Sep 18. [Epub ahead of print] BACKGROUND::Patients with multiple sclerosis (MS) demonstrate thinning of...

Free up your diary

I had posted about keeping you diary free for a special event in November 28th to be held a Barts, but unfortunately we have not been able to get any Members of Parliament to attend, which we wanted. The main reason is that it is being held on a Thursday night when parliament is in session (I suspect they are all too chicken). ProfG therefore wants to postpone the event until the New...

How Not to Win an Award

We (Giovannoni & Team G) have been nominated for the MS Society 2013 Awards in the category of MS Digital Media of the Year.

After outburst (below), I would just like to say congratulations to Shift.ms or Barbara as Prof G blows our chance.

Anyway should be a fun day.

I wonder who will attend? JLS split this year!

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