Version 4 of ECTRIMS brain atrophy infographic

Version 4 brain atrophy infographic; comments please. #MSBlog #MSResearch

“The following is version 4 of my brain volume infographic that I will be using at the blogging session at ECTRIMS. I still have time for changes. Any more recommendations would be appreciated. Thank you.”

About the author

Prof G

Professor of Neurology, Barts & The London. MS & Preventive Neurology thinker, blogger, runner, vegetable gardener, husband, father, cook and wine & food lover.


  • I read an interesting interview with KOL , Dr. Timothy Vollmer that points in the same direction. How far away are we before neuroprotective drugs will be first-line treatment?

    " Dr. Vollmer points out that most disease activity is subclinical. "Physicians can't tell by looking a patient what is happening in their brain. —– If we allow the management to be governed by symptoms we are trading off function in later life. The goal should be to preserve function now so as to reduce lifelong disability. Disability has been correlated with reduced brain volume on MRI, so we can rank the drugs on their effect on inflammation and brain atrophy. "


  • The information on the slides is factually accurate, but it does make a depressing read for someone with MS. DMT's at an early stage, or stem cell treatmens are our only hope. But is there anything we can do to help ourselves?
    To give us a bit more optimism, will there be any accompanying documents setting out the background to the slides? e.g. excercise may reduce the 8 year shortfall in life expectancy, or how can we adopt to a sedentary life yet still maintain fitness.
    In respect of divorce, is it the partner of the MSer or the MSer themselves who initiate the split?

    • Andrew, you are already on the right track. you are trying to help yourself. I had very active RRMS at 21. I did whatever exercise that was suitable, not too much. After I was told to give up Badminton by neuros, I learnt a language to GCSE. I've never smoked and my diet has always been healthy. I had a very stressful job. I only became SPMS after a 3rd operation in 2 years for cancer. I have never taken DMTs, only steroid twice for optic neuritis. This week is the 35th anniversary of my diagnosis. It has been a struggle, but I have no regrets. Concentrating on things you can do is so important. I was given exercises to do whilst sitting by a physio only last week. I hope you find a way that helps you.

By Prof G



Recent Posts

Recent Comments