ArchiveOctober 2013

Shift MS reports

You may have seen clips of Team G and other members fron UCLP in the MS reports by Shift MS

Here is the full interview of Prof B talking to Mariam
and then Prof G…as you can see the minute per answer (look at the egg-timer) just wasn’t going to happen.

NB. International Collaborative has been rebranded as the MS Alliance

View it bit by bit

Glaterimer acetates inhibits Macrophage function

Thamilarasan M, Hecker M, Goertsches RH, Paap BK, Schröder I, Koczan D, Thiesen HJ, Zettl UK. Glatiramer acetate treatment effects on gene expression in monocytes of multiple sclerosispatients. J Neuroinflammation. 2013 Oct;10(1):126. [Epub ahead of print] BACKGROUND: Glatiramer acetate (GA) is a mixture of synthetic peptides used in the treatment of patients with relapsing...

Designing Team G

How a designer is helping researchers explain MS science What makes Team G different..well many things But Art, Design and Science can mix.  Alison a Designer in our group, and a student, has been instrumental in the development and implementation of many of our public engagement activities as well as working to improve our patient experience. Read More on the Post from the MS Trust (Click...

Are you sleeping?

Veauthier C. Younger age, female sex, and high number of awakenings and arousals predict fatigue in patients with sleep disorders: a retrospective polysomnographic observational study. Neuropsychiatr Dis Treat. 2013;9:1483-1494. Epub 2013  BACKGROUND:The Fatigue Severity Scale (FSS) is widely used to assess fatigue, not only in the context of multiple sclerosis-related fatigue, but...

Mesenchhymal Stem cells Less active on Autoimmuners

Ben-Ami E, Miller A, Berrih-Aknin S. T cells from autoimmune patients display reduced sensitivity to immunoregulation by Mesenchymal Stem Cells: Role of IL-2. Autoimmun Rev. 2013 Oct. doi:pii: S1568-9972(13)00171-7. 10.1016/j.autrev.2013.09.007. [Epub ahead of print] Mesenchymal stem cells (MSCs) are multipotent progenitor cells which have been shown to possess broad immunoregulatory and...

Does having JC virus affect the choice to stay on Tysabri

Lonergan R, Kinsella K, Kelly S, Duggan M, Scott J, O’Rourke K, Lynch T, Hutchinson M, Tubridy N, McGuigan C. Does JCV antibody positivity encourage cessation of Natalizumab therapy in Multiple sclerosis. J Neurol Neurosurg Psychiatry. 2013 Nov;84(11):e2 BACKGROUND: Natalizumab, a monoclonal α-4-integren receptor antibody, is an effective immunomodulator in highly active...

Pencil in the Date

You have been asking when is the Next Research Day in London will be.  Well I cannot yet say for definite because Team G are not doing the organization. Next time it is being done by our friends in UCLP at University College London.  They have yet to definitively select the venue and find the funds to support the day.Time is ticking.. At present they have been looking into the...

CD8 can be nothing cells

Leuenberger T, Paterka M, Reuter E, Herz J, Niesner RA, Radbruch H, Bopp T, Zipp F, Siffrin V. The Role of CD8+ T Cells and Their Local Interaction with CD4+ T Cells in Myelin Oligodendrocyte Glycoprotein35-55-Induced Experimental Autoimmune Encephalomyelitis. J Immunol. 2013 Oct. [Epub ahead of print]T cells have an essential role in the induction of multiple sclerosis and its animal model...

Happy with Tecfidera

Kappos L, Gold R, Arnold DL, Bar-Or A, Giovannoni G, Selmaj K, Sarda SP, Agarwal S, Zhang A, Sheikh SI, Seidman E, Dawson KT.Quality of life outcomes with BG-12 (dimethyl fumarate) in patients with relapsing-remitting multiple sclerosis: The DEFINE study. Mult Scler. 2013 Oct 22. [Epub ahead of print] BACKGROUND:Oral BG-12 (dimethyl fumarate), approved for the treatment of the relapsing...

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