MS Roadshow: Southend 7th October 2013

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MS Roadshow at Southend this evening. #MSBlog #MSResearch


“In response to an email I have posted the advert for tonight’s MS Roadshow. We hope to see you there. Please make sure you RSVP; the local organisers need to know numbers. Thank you.”

About the author

Prof G

Professor of Neurology, Barts & The London. MS & Preventive Neurology thinker, blogger, runner, vegetable gardener, husband, father, cook and wine & food lover.

2 comments

  • Prof G, I asked this question last week but you never responded. I'll ask again:

    Prof G, can you tell me if the occurrence of MS is less common in mixed-race people? I ask because I thought that human cross-pollination creates a more dynamic gene pool, meaning stronger biological characteristics.

    Yet at your ECTRIMs debate, a scientist said that the only case of MS he's seen in a person from the far east was a mixed-race Philippine-French girl. He claimed it was the French component that was responsible for her developing MS.

    Are mixed-race folk more susceptible to MS.

  • How do you see your mix could it be more or less.

    The higher risk areas are in white Northern Europeans and less in say Black Africans and there you have the environmental and the genetic interactions. So if you are mixed race do you have less susceptibility than white or more susceptibility than black so are you a glass half full or empty person.

    Remember there are MS risk genes like HLA-DR2 serotypes. This is common in white Europeans so getting rid of that in mixed race children by having a baby with someone where the risk genes are less common then the risk should drop. However genes are only a part and the environment is important so if you look at second generation of immigrants in UK their risk is much higher than first generation telling us it is not all genes.

    In East London I see plenty of non white (Europeans or non-European Dissent). In the surveys from US military there is an increase of MS in Black/African American soldiers.

    In the far East the NMO variant appears to be more common.

    The MS characteristic may be a product of a "stronger" biological characteristic e.g. the genes may make you react better to infections but the consequence is the chance of autoimmunity. There is no MS gene but the genes that come together to increase risk of MS are probably beneficial for the general population

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