You keep telling TeamG to get off its bum and start reporting on repair strategies. However this study suggests that one of the most important strategies to promote repair is to stop further damage occurring and then let the natural repair mechanisms kick in.
This was shown using tysabri is EAE. The big question is does this happen in MS?
The answer should be to hands. Some pathologists could have the answer, but have they looked?
Tysabri can be very effective at stopping MRI lesions and relapses,which should allow repair to occur if this is the case.
Unfortunately Tysabri also kills some MSers because of PML. Therefore how many demyelinated MS lesions are there compared to how many lesions that are remyelinated. This can determine if effective tysabri allows remyelination, or is demyelination persistent?
There clearly are some demyelinated lesions in PMLers based on one study but have pathologists really looked for remyelination.
This is an experiment that needs doing urgently!