Can we get repair in MS? Heres an old TED (Click on Old Ted for a working link to the video) from our
Friend Dr Chandran from Edinburgh who has been leading
some of the UK effort in this Area.
Troll-Free Zone.
Although we appear to be a Troll-Free Zone, we still get the odd person spilling some bile. Their posts however end up in spam or go straight to the bin. This online report about Internet trolling shows that they (trolls) show narcissism (egocentrism and preoccupation with prestige), machiavellianism (tendency to deceive and manipulate), psychopathy (lack of empathy and inhibition), and sadism...
Remyelination of cortical lesions may not always repair
Rodriguez EG, Wegner C, Kreutzfeldt M, Neid K, Thal DR, Jürgens T, Brück W, Stadelmann C, Merkler D. Oligodendroglia in cortical multiple sclerosis lesions decrease with disease progression, but regenerate after repeated experimental demyelination. Acta Neuropathol. 2014 Feb 25. [Epub ahead of print] Cerebral cortex shows a high endogenous propensity for remyelination. Yet, widespread subpial...
MS is increasing in New Zealand
Alla S, Pearson J, Debernard L, Miller D, Mason D. The Increasing Prevalence of Multiple Sclerosis in New Zealand. Neuroepidemiology. 2014 Feb;42(3):154-160. [Epub ahead of print] Background: New Zealand (NZ) has a high prevalence of multiple sclerosis (MS). Worldwide, the prevalence of MS appears to be increasing. Objectives: To review all published prevalence studies undertaken...
Not all viruses are associated with MS
Hon GM, et al. J Clin Neurosci. 2014 prevalence of human herpesvirus-6 and varicella zoster virus in blood of multiple sclerosis Herpesviruses, including human herpesvirus-6 and varicella zoster virus, have been implicated in the disease aetiology of multiple sclerosis. These viruses are capable of reactivation, reminiscent of the relapsing-remitting nature of multiple sclerosis. However...
Pain in MS
Fernández-de-Las-Peñas C, Ortega-Santiago R, Ortíz-Gutiérrez R, Caminero AB, Salom-Moreno J, Arendt-Nielsen L. Widespread Pressure Pain Hypersensitivity in Patients with Multiple Sclerosis with and Without Pain as Sign of Central Sensitization.Clin J Pain. 2014 Feb 12. [Epub ahead of print] OBJECTIVE:To determine the presence of widespread pressure hyperalgesia in multiple sclerosis (MS)...
What use is rehab?
What components of rehabilitation are helpful from the perspective of individuals with multiple sclerosis? Salminen AL, Kanelisto KJ, Karhula ME. Disabil Rehabil. 2014. [Epub ahead of print] Purpose: To investigate the helpful components of rehabilitation from the point of view of people with multiple sclerosis (MS). Methods: Sixteen focus groups were conducted for 68 adults with MS, who...
Laquinimod trìal data published 2 Years after the contents released to Investors
Vollmer TL, et al. J Neurol. 2014 A randomized placebo-controlled phase III trial of oral laquinimod for multiple sclerosis. The phase III placebo-controlled BRAVO study assessed laquinimod effects in patients with relapsing-remitting MS (RRMS), and descriptively compared laquinimod with interferon beta (IFNβ)-1a (Avonex(®) reference arm). RRMS patients age 18-55 years with Expanded Disability...
Being Unhelpful
You are given the option of saying posts are unhelpful, helpful; or very helpful
Recently we have been getting a few too many “unhelpfuls”.
Whilst this may be the last option open to a troll, you may have some justified reason for this.
In the interests of feedback it would be helpful to say why it is unhelpful., remembering we are about Good and BAD news…
CCSVI Saturday
All is quiet on the CCSVI Front Not much to Report More next month or Maybe Not? Scalise F, Novelli E, Farina M, Barbato L, Spagnolo S.Venous Hemodynamic Insufficiency Severity Score variation after endovascular treatment of chronic cerebrospinal venous insufficiency. Phlebology. 2014 Feb 14. [Epub ahead of print]...