Spagnolo S, Scalise F, Barbato L, Grasso MA, Tesler UF. Bilateral Surgical Reconstruction for Internal Jugular Veins Disease in Patients With Chronic Cerebrospinal Venous Insufficiency and associated Multiple Sclerosis. Ann Vasc Surg. 2014. pii: S0890-5096(14)00179-4

Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular condition characterized by morphological alterations involving efferent cerebral vascular paths. CCSVI has been implicated as a contributing factor to multiple sclerosis (MS) but this theory is highly controversial. We report three cases of CCSVI patients with MS who had undergone internal jugular veins (IJVs) angioplasty to restore vessels patency. All patients reported significant symptomatic improvement after angioplasty until symptoms recurred following restenosis of the treated IJVs. Surgical IJVs reconstruction was performed. Patients’ symptoms gradually improved and the benefits were maintained at the one-year follow up.

Some positive news on the day, I will no doubt meet a few fans of the procedure at MS life 2014. 

If it is so clear cut, then why have the trials so far been unconvincing or stopped?  Hopefully we will soon hear from more definitive trials.

The following is the latest Google Trends on CCSVI.”

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