Happy News Tuesday

 “Everything’s Amazing and we are all made out of Stardust”

Had a lab meeting yesterday and it was great, we got a new paper accepted and this was great. We had data from the INSPIRE  trial which was awesome and got rid of autoimmunity which was amazing. The optic neuritis trial is fantastic and we’ve sorted out mitochondrial problems to stop nerve damage, which is great. Then the remyelination studies were so ace, so we’ll have the cure in a week. In addition the  FDA have relaxed its rules so that academic neuros don’t need to do the same studies as required of Pharma, which is great and then…I fell out of bed and woke up.

What’s real and what’s fantasy…. 

Some people complain that the blog is too much doom and gloom and want some more up-beat posts. Some times we make the news, but often, we report it. This can be good, bad and other news. 

Science isn’t all happy, happy..sorry to say.

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  • Mouse, your fall out of bed was probably due to the 10 cans of lager you consumed after your chinese take-away.

    We're not here for fantasy stories, but apart from Alemtuzumab, it's not been a great year for breakthroughs. As the years go by, I'm starting to realise that research is a world in its own and often disconnected from the patients who have the real disease. You'd think that as each year ends we'd get a better understanding of the disease, instead, like unpicking an onion, what is revealed is more horror and less understanding. What's Team G's 5 year and 10 year strategy? What does Team G hope to achieve by 2020? The number of peer reviewed published articles, PHD students, attendance at international conferences, dead mice is irrelevant to me. I need something to make me better / a bit better. If you or someone you knew had this disease, you'd have a good sense of the desperation.

    • While I second some of your points I would not like to pick on Team G – they are doing us a service with this blog.

      However, I think Team G should concentrate on some things that already show promise and drive the research home without distracting itself further like biomarkers, charcot project, oct in ms diagnosis and brain atrophy.

  • Blimey, I was planning to head off down the pub in celebration but then I got to the end of the paragraph.

  • Any wish to comment on the new discovery of an alzheimer's test as reported by the Guardian today?

    Would it make sense to apply the test in MSers to see if the neurodegeneration overlap?

  • It is easy to forget even bad news increases our understanding. It is not like reality changes just because we don't understand it yet (I know this is a philosophical point, but science rests on it). The bad results for those of us with MS are happening, and even the negative results yield knowledge if we analyze them. Yes, the scientific process is slow, and then the steps between lab and market slow us further.

    I understand the anger, and I share the frustration. However, without the proper scientific method we end up with more bee sting therapies and stents which seem to offer little by way of cure for the masses.

  • "Last year there were 100,000 peer-reviewed papers on the brain. What we're missing is a plan, to work with all the data that we're generating” – Prof Henry Markram Professor of Neuroscience, EPFL, Switzerland

    Looks like it's not just MS research that just churning out tonnes of research papers. Brain research is a licence to print money (researcher salaries, consulting fees, international freebies). Did you see the progress they've made in Altzeimers research. No – me either.

    By the way blogs don't make me walk better or look forward to the future. I need treatments on the shelf today – not in 10 years time.

  • See MD, that wasn't so hard to put on your rose tinted glasses, was it? Now we can tackle the persistent problems in the middle east 🙂

  • Wouldn't we all rather take a wonderpill .. decent research is the next thing, and I'm grateful for this blog's efforts to communicate that.

  • Mouse,

    d-reams's hit was "thing can only get better" ….. Given your inside knowledge of MS research, is this likely to be the case for MSers?

    If your work does improve my lot, I promise to buy you a Metallica concert ticket, 12 cans of your favourite lager, and some extensions to add to your pony tail.



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