ArchiveFebruary 2015

Genetics of thin brains give ideas to control progression

Matsushita T, Madireddy L, Sprenger T, Khankhanian P, Magon S, Naegelin Y, Caverzasi E, Lindberg RL, Kappos L, Hauser SL, Oksenberg JR, Henry R, Pelletier D, Baranzini SE. Genetic associations with brain cortical thickness in multiple sclerosis.Genes Brain Behav. 2015. doi: 10.1111/gbb.12190. [Epub ahead of print] Multiple sclerosis (MS) is characterized by temporal and spatial dissemination...

Shift work gives you MS

Hedström A, Åkerstedt T, Olsson T, Alfredsson L.Shift work influences multiple sclerosis risk. Mult Scler. 2015 Feb. pii: 1352458514563592. [Epub ahead of print] BACKGROUND:An association between working shift at a young age and subsequent risk for multiple sclerosis (MS) has been observed.OBJECTIVE:To investigate whether this finding could be replicated, and to further explore the influence...

Causing MS by blockade of TNF

Napolitano M, Balato N, Ayala F, Cirillo T, Balato A. Multiple sclerosis following anti-tumor necrosis factor-alpha therapy for psoriasis: First case in Italy? Case report and review of the literature. G Ital Dermatol Venereol. 2015 Feb 18. [Epub ahead of print] The use of Tumor Necrosis Factor alpha (TNF–α) antagonists has profoundly improved clinical management of psoriasis and other...

MS doesn’t stop you getting pregnant

Roux T, Courtillot C, Debs R, Touraine P, Lubetzki C, Papeix C. Fecundity in women with multiple sclerosis: an observational mono-centric study.  J Neurol. 2015. [Epub ahead of print] Multiple sclerosis (MS) is a neurological disease mostly affecting women of childbearing age. When counseling MS patients, many questions arise on the reciprocal influence of MS and pregnancy. However...

Should animal studies be run like human clinical trials?

Some people think that animal studies should be like clinical trials and registered in a public data base before the work is done. This was the idea at a science meeting that I have recently attended If you are a research scientist you would have to say what you are doing before you do it, what would be the primary outcome that you want to find and you would say how you are going to do it so you...

Parasite eggs not much use in controlling MS

Voldsgaard A, Bager P, Garde E, Åkeson P, Leffers A, Madsen C, Kapel C, Roepstorff A, Thamsborg S, Melbye M, Siebner H, Søndergaard H, Sellebjerg F, Sørensen PS.Trichuris suis ova therapy in relapsing multiple sclerosis is safe but without signals of beneficial effect. Mult Scler. 2015. pii: 1352458514568173. [Epub ahead of print] BACKGROUND: An observational study has suggested that...

Peoples Strictly-Vote Trishna

#MS Research Vote #Trisha @ #Peoples Strictly Six inspirational but everyday heroes and heroines have been confirmed to take part in BBC One’s The People’s Strictly for Comic Relief and fulfil every Strictly fan’s dream. Whilst we should remain impartial…sod it..Come On Trishna! For a Non-British Audience how do you describe Peoples Strictly.  Well it is a twist of a television light...

TeamG news developing drugs

As soon as we published the prospect of developing a new drug for symptom control. You said “As Del Boy (Prof G) said to Rodney (Prof M) – we’ll be millions. I better invest in beer companies and heavy metal record labels for when you hit the big time. Prof G can give his countryman Berlosconi a run for his money”. Maybe we are psychic, as I made this figure last weekend...

TeamG Research is not all esoterric

MD2 in response to a comment recently (16:2:2015) wrote “we have some great research coming down the pipe that will stick two fingers up to the negative crowd;-)”                              Today is the part of the proof …but these two fingers are not exactly the response I was thinking:-).  But...

TeamG Research from Idea to MSers

#MSResearch #MSBlog. TeamG & Friends develop new MS drug for #spasticity Many blog sites get conned into doing advertising for Company X or Company Y following press releases by announcing that Company X or Company Y, will start trials in MS as soon as they have financing, hoping for some more shareholder investment. So now is the time to make a company pitch, but we are not after your money...

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