ArchiveMay 2015

ClinicSpeak: Fingolimoders need to be aware of opportunistic infections

If you are on fingolimod please be vigilant about infections, including opportunistic infections. #ClinicSpeak #MSBlog #MSResearch “In response to an anonymous comment on the Natalizumab retinitis post yesterday. I think it is appropriate to warn all MSers on fingolimod to be vigilant as well about infections and opportunistic infections.” “The two case studies below highlight...

So the Blog is a Blockbuster Drug

Rieckmann et al. Achieving patient engagement in multiple sclerosis: A perspective from the multiple sclerosis in the 21st Century Steering Group. Mult Scler Relat Disord. 2015; 4:202-218. While advances in medicine, technology and healthcare services offer promises of longevity and improved quality of life (QoL), there is also increasing reliance on a patient׳s skills and motivation to...

Prognosis after clinically isolated syndrome

Jokubaitis VG, Spelman T, Kalincik T, Izquierdo G, Grand’Maison F, Duquette P, Girard M, Lugaresi A, Grammond P, Hupperts R, Cabrera-Gomez J, Oreja-Guevara C, Boz C, Giuliani G, Fernández-Bolaños R, Iuliano G, Lechner-Scott J, Verheul F, van Pesch V, Petkovska-Boskova T, Fiol M, Moore F, Cristiano E, Alroughani R, Bergamaschi R, Barnett M, Slee M, Vella N, Herbert J, Shaw C, Saladino ML...

ClinicSpeak: Natalizumabers PML is not the only viral infection you need to worry about

Natalizumabers PML is not the only viral infection you need to worry about. #ClinicSpeak #MSBlog #MSResearch “The following is a sobering reminder that we need to remain vigilant for other opportunistic CNS (central nervous system) infections in MSers on natalizumab. The case report below is of a MSer developing a severe VZV (varicella zoster virus) retinitis with significant visual loss...

Headache, hmm?

Neurol Sci. 2015 May;36(Supplement 1):75-78. Headache in multiple sclerosis and autoimmune disorders. La Mantia L, Prone V. The headache may be considered among the neuropathic pain syndromes of multiple sclerosis (MS). Several studies have showed that it is more frequent in MS patients than in controls or general population. Headache may occur at the pre-symptomatic phase, at clinical onset and...

ClinicSpeak: benign MS is a misnomer

Should we stop using the term benign MS? #ClinicSpeak #MSBlog #MSResearch “The study below on benign MS illustrates a point that we have made many times before; benign MS is a very difficult call. A significant proportion of benign MSers have cognitive impairment and associated fatigue, depression and anxiety. Therefore is it correct to simply call someone as having benign disease based on...

Dr Giles does Diagnosis

MS Society Press Release: World MS Day – Diagnosis Story Survey reveals many people are misdiagnosed and live in uncertainty for years before MS diagnosis ·        1 in 4 people with MS misdiagnosed with having a trapped nerve ·        1 in 10 people with MS told they’d had a stroke...

Asthma and MS…Little effect on the disease course

Manouchehrinia A, Edwards LJ, Roshanisefat H, Tench CR, Constantinescu CS.Multiple sclerosis course and clinical outcomes in patients with comorbid asthma: a survey study.BMJ Open. 2015 May 20;5(5):e007806. doi: 10.1136/bmjopen-2015-007806. OBJECTIVE:To determine if comorbid asthma is associated with accumulation of multiple sclerosis (MS)-related impairment and disability.METHOD:We sent a...

Anyone got a home for a few million mice?

Recently we sent you to an anti-vivisection website campaigning against animal experiments in Europe. So in the spirit of balance there are sites that support animals research such as Speaking for Research..  There is a debate on the use of animals in research A transcript and summary of the key points made by the European Animal Research Association and put together the key points that were...

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