ArchiveJuly 2016

Game over the ref has stopped the transfer market

The Research Excellence Framework (REF) is a method of how the UK Government assesses Reserach Excellence and this dictates how it gives £2 billion a year to Higher Education Centres. This occurs every 5-6 years and the next one in in 2020/2021. In the past the Universities have selected who they return (you only get paid for those you submit), based on their performance which influences their...

ClinicSpeak: what matters to you?

Are you happy with the way you are treated? Have your say! #ClinicSpeak #MSBlog #HaveYourSay “I typically read the BMJ on my way to work on a Monday morning and the NEJM on a Thursday morning. Hence my frequent posts from the BMJ and NEJM on a Monday and a Thursday, respectively. I am no different to most and would be the first to admit that I am a slave to habit. However, this week’s...

Benign MS

Zivadinov R, Cookfair DL, Krupp L, Miller AE, Lava N, Coyle PK, Goodman AD, Jubelt B, Lenihan M, Herbert J, Gottesman M, Snyder DH, Apatoff BR, Teter BE, Perel AB, Munschauer F, Weinstock-Guttman B. Factors associated with benign multiple sclerosis in the New York State MS Consortium (NYSMSC).BMC Neurol. 2016 Jul 15;16(1):102. doi: 10.1186/s12883-016-0623-2. BACKGROUND:This retrospective...

CrowdSpeak: using survival analysis makes Charcot 2 cheaper

An alternative power calculation for the Charcot 2 project.  #MSResearch #CrowdSpeak #Crowdacure #MSBlog “In response to a comment by ‘Stats is my name‘, (Friday, July 29, 2016 9:36:00 pm): ‘But you can’t compare shedders at 1 month vs shedders at 3 months. You can only compare like with like so you should use the numbers by time period’. This got me...

Need for Spasticity Agents

Rønning OM, Tornes KD.Need for symptomatic management in advanced multiple sclerosis. Acta Neurol Scand. 2016. doi: 10.1111/ane.12631. [Epub ahead of print] OBJECTIVE:A majority of patients with advanced multiple sclerosis (MS) need symptomatic treatment. Many MS-related symptoms may not be recognized and thus are not treated. We conducted a study to estimate the prevalence of inadequate...

The Sixth Amendment-Spasticity trial

The Sixth Amendment of the US constitution guarantees the right to a Speedy Trial and Impartial panel of Assessors (Jury).We want to do the same.  Double blind trials have a impartial set of assessors who are there to monitor the good and bad effects of any test drug but how do we make it more speedy…..simple its the Sixth Amendment.  Every time you want to change anything in the...

CrowdSpeak: Why am I a bottleneck?

Thank you we now have our power calculations for the Charcot 2 project? #MSResearch #CrowdSpeak #Crowdacure #MSBlog “David Holden successfully completed all the lab work on the saliva samples and sent me the spreadsheet several weeks ago. I only managed to analyse them two days ago. We have achieved what we wanted to with the samples and now know how many people with MS shed virus in...

Learning from other conditions may teach us something-Obrigado

Meyer S, Woodward M, Hertel C, Vlaicu P, Haque Y, Kärner J, Macagno A, Onuoha SC, Fishman D, Peterson H, Metsküla K, Uibo R, Jäntti K, Hokynar K, Wolff AS; APECED patient collaborative, Krohn K, Ranki A, Peterson P, Kisand K, Hayday A.AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies. Cell. 2016 Jul 14. pii: S0092-8674(16)30792-9. APS1/APECED patients...

ThinkHand: what iconic image captures hand function best?

There is a PROM for hand function; what do you make of it? #ThinkHand #MSBlog #MSResearch “Thank you for engaging with our #ThinkHand Campaign; response to the survey has been excellent. We are hoping to get more than additional 400 responses by mid August for our ECTRIMS poster.” Loading… “In addition, to the survey there are another two things we need help with from this...

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