What interests you this year?
As soon as the microbiome (Gut Microbe) appeared it was obvious that the scammers would be there to make money off vulnerable people.
People will asked to pay money to have their bowels cleared and the they have to eat a feacal extract to change their microbiome. Ker-ching.
Academics would then follow do a trial and show that it doesn’t really work…OK that’s me just guessing. However they will do a study to see if it works and the MS Socieites spend aload of money.
It is happening a trial of feacal transplant ….. Yep you get your bowels cleared and then you eat it.
groups. One group will receive FMT by rectal enema, while the other group will receive treatment as per standard
of care (control group) for the first 6 months. Thereafter, the early intervention group will no longer receive FMT
and the initially control group will receive FMT for the remaining 6 months. A 3rd group of healthy volunteers will
be a reference control. Primary outcome will be peripheral blood cytokines measured by Luminex assay. As
secondary outcomes blood DNA bacteria and urinalysis to evaluate gut permeability, head MRI as a safety
marker and trial feasibility metrics.
Results: Eight patients have already been enrolled to this study, 4 (50%) females and 4 (50%) males. Mean age
of disease onset is 32 years old (22 – 40). Mean current EDSS is 4.0 (1.5 – 6.5). Patients manifested their MS
symptom in average 20 years ago (7-44). All except two are currently using disease modifying therapy.
Conclusions: This proof of concept, first in humans, independent pilot study will shed light on the relationships
between gut bacteria and MS. We present here study design and preliminary baseline demographics, and discuss
its possible impact on disease inflammation to guide future large-scale studies.
Many people have been conned to part with their hard-earned cash They no doubt give you some R & R and fed someone elses number two’s. Canada forked out a few million to rebuff the CSSVI idea and this study is looking at changes in the microbiome
In this study from Canada you get an enema, but at the AAN, you wont get result for a few years? So do we want to know that a trial is occuring.
But in this study from Harvard, They are taking a Probiotic.
Synergism is a word that is often overused in science. Synergiism means more than the additive effect of two things. What is the evidence for this?. Maybe the probiotic influences immunity but we need to see the effect on clinical parameters