ArchiveAugust 2018

What’s a prodrome and what does it mean in MS?

  MS is a disease of young adults who are often diagnosed in their twenties.  However, epidemiology studies suggest that you develop the risk for MS in your mid teens. So can MS be picked up before diagnosis is there a Prodrome, which is an early symptom indicating the onset of the condition? We know from exam results done in Argentina, that people destined to develop MS, can do a bit worse...

Parkinson’s in Multiple Sclerosis

Neurol Sci. 2018 Aug 16. doi: 10.1007/s10072-018-3531-y. [Epub ahead of print] Parkinsonism and multiple sclerosis, what is behind? Uysal Tan F Letter to the Editor Dear Editor, The awareness of the coexistence of both diseases in some patients resulted in an ongoing debate on either causal or coincidental relationship between multiple sclerosis (MS) and parkinsonism. Present data offers some...

Guest post: Primary Progressive MS Research: Treatment Outcomes

This is a repost from MStranslate, with kind permission from Brett Drummond. PPMS is characterised by a steady worsening of disease or accumulation of disability from onset without any lengthy periods of stability or ‘remission’. Some people with primary progressive MS may also experience acute attacks of active disease, commonly referred to as relapses, during which symptoms are exacerbated or...

ProfG a Week in TwitterLand

  ProfG has taken to twitter to comment on posts.Should we consider a feature on his comments on the blog as it is is clear many people can’t we bothered with Twitter?Gavin GiovannoniThis study suggest that the anti-JC virus antibody index will be difficult to interpret and use to risk profile MSers on rituximab or ocrelizumab as it affects antibody production. Anti-JC virus antibody...

Evidence against oligoclonal bands being important?

As you may realise, I am sometimes critical of my colleagues who tend to follow dogma, without question. This of course does me no favours with my colleagues. Maybe I should just say everything is “Great” or “Super”, like I’m part of  some 1970s Sitcom :-0 For many, many years my colleagues have been hunting for the autoantigen in MS. They have got nowhere...

Guest post: Does degradation of brain fats cause MS?

This is to let you know about a research project based on a novel idea of how MS develops. I am a pathologist, and have spent most of my career on medical research. I am returning to researching on MS after a long period of working on the arterial disease that causes heart attacks and strokes. The reason for my return to MS work is that I believe that MS may develop in a way similar to arterial...

Guest Post: Language and MS: Why Our Words and Stories Matter

Question. Those with multiple sclerosis: do you remember the exact words your neurologist used to break the news of your diagnosis? And those on the other side: MS neurologists and health professionals. Can you recall the most difficult conversation you’ve had with someone with MS and the words you used? Thought so. Words matter in medicine – especially with a disease like multiple...

Neuroinflammation associated with nerve damage in progressive MS

This study looks at neuroinflammation. Specifically the fact that the development of treatments for progressive MS is hampered by the lack of suitable biomarkers that can accurately detect and monitor intrathecal inflammation (inflammation which occurs within the spinal theca, which is a sac containing the cerebrospinal fluid which provides nutrients and buoyancy to the spinal cord)...

How big is your need to exercise?

The evidence that exercise and I mean regular exercise is good for you is so overwhelming that it is hard to argue against the science. What I mean by this is that almost everyone accepts exercise as being good for the general population and for people with MS. The downside is that some MSers are so disabled and/or have so much fatigue that they find it difficult to exercise. I am prepared...

My Tibetan Odyssey: In search of Gods in the highest of places

“Mountain climbing as an obsession is a selfish endeavor, and there’s just no way to get around that fact”        -Beck Weathers in ‘Left for Dead’ on the 1996 Everest disaster. I spent the better half of July/August in Tibet, which boasts some of the tallest peaks on Earth. Like many before me I was inspired to witness with my own eyes what all the hype was...

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