Combination of cannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), mitigates experimental autoimmune encephalomyelitis (EAE) by altering the gut microbiome. Al-Ghezi ZZ, Busbee PB, Alghetaa H, Nagarkatti PS, Nagarkatti M. Brain Behav Immun. 2019 pii: S0889-1591(19)30647-6. doi: 10.1016/j.bbi.2019.07.028. [Epub ahead of print]
There you have it cannabis works because it affects your microbiome.
Dear Oh Dear. We have given up on cannabinoid related research as the neuros kept on messing up the clinical trials and our voice has been lost under the sea of tosh animal studies.
Since we first showed that cannabis has the potential for symptom control, this work has been used to justify EAE studies on immunomodulation. Funnily they cite this and ignore our work saying that it was not immunomodulating at sensible doses that did ot make animals super-high. Avoid this and it is not immunomodulating. However, we have seen paper after paper on this and we have been airbrushed from history.
Do humans who smoke cannabis get massively immunosuppressed…Answer = No
Do humans with MS who smoke cannabis still have relapses? You tell me ?Cannabis is the Aspirin of the 21st Centrary is after all
However, it now works by changing microbiome?