The worst thing about COVID for many women,and perhaps a few men is Fifty shades of Grey. Indeed Roots will not be a story about Kunta Kinte but the horror show of being isolated to many weeks on end. However, I am sure you can still buy it in a bottle. But in contrast many women will be are saying thank heaven for COVID-19…
This seems a bit strange, but it appears that one of the signs of the viral infection is that your sense of smell goes. So you don’t have to smell the old man’s (husband) smelly socks and gas:-). In other people they have no taste…but hey just go down the local high street and you can see that from what people are wearing :-). Indeed it is claimed that loss of smell may be the only sign of the infection and if you recognise this and self-isolate it may help stop you infecting other people.
However be warned that sometimes you can loose your sense of smell due to MS. Olfactory dysfunction in multiple sclerosis.Atalar AÇ, Erdal Y, Tekin B, Yıldız M, Akdoğan Ö, Emre U. Mult Scler Relat Disord. 2018;21:92-96.
It appears that many people are unaware that they are infected with the SARS-Cov-2 virus causing COVID 19 and then you also have a few idiots who don’t think about their actions. I have had to laugh at some of the BBC news programmes, where the reporter is talking about how well social distancing is working, when in the background you can see two or three people talking, inches/centimeters apart:-). It is clear that there are many asymptomatic people and they will be infecting people until their immune system rids them of the virus. This has been models to be about >85% although it may be lower based on other studies. So remember to keep your distance.
Testing in the UK is woefully inadequate. ProfG , ProfK, NDG, Dr M&M and all the other health care workers including our great nurses, who not only deserve a National clap, but I am sure they would really appreciate a payrise. It is terrible that so many of the nurses we train leave the profession within a couple of years.
These guys whose only protection may be a smile deserve to be tested on a regular basis, not only to know if they have the virus but also to now if they have had the virus. I wish Dr Angry and I had generated a test, before our labs were shut down. Yes, other people are doing to do this, and indeed it has already been done, but we could have made a test for our boys and girls at BartsHealth and done something of the National Effort.
If you suspect you have the virus you self-isolate for 7 days (according to the Current Government practise), which is rather inadequate in my opinion, as peope can infect for more than 7 days. In Italy they apparently screened a whole town of 3,000 people and found 66 People infected, who were asked to self -isolate for 14 days at a time 6 were still positive for the virus.
The European Centre for Disease Control say
SARS-CoV-2 virus can initially be detected 1–2 days prior to symptom onset in upper respiratory tract samples; the virus can persist for 7–12 days in moderate cases and up to 2 weeks in severe cases . So if you have the disease obvious make sure you stay out of circulation
It’s not all doom and gloom. Proper trials need to be done, but
Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. Gautret P et al. J Antimicrob Agents. 2020 Mar 20:105949.
Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro.Liu J, Cao R, Xu M, Wang X, Zhang H, Hu H, Li Y, Hu Z, Zhong W, Wang M.Cell Discov. 2020 Mar 18;6:16
Chloroquine is a zinc ionophore.Xue J, Moyer A, Peng B, Wu J, Hannafon BN, Ding WQ.PLoS One. 2014 Oct 1;9(10):e109180
Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture. te Velthuis AJ, van den Worm SH, Sims AC, Baric RS, Snijder EJ, van Hemert MJ. PLoS Pathog. 2010 Nov 4;6(11):e1001176.
Why you don’t want covid 19
COVID-19 pandemic: triage for intensive-care treatment under resource scarcity. Swiss Academy Of Medical Sciences. Swiss Med Wkly. 2020 Mar 24;150:w20229.