COVID Breakfast…Daddy what did you do in the COVID19 War?

C

I’m rather glad I won’t have little voices asking this

My answer would have to be “Sat on my Ass doing nothing, when there are people in the frontline doing their bit……. and dying”. In the 1914-1918 era if you did nothing you would be given a white feather, I’ve already got a duck-down pillow by now.

Yes a bit of melodrama, but it is frustrating to be locked away, when you have things to do, and you can’t do anything, even if it is COVID19 related. Unless it is part of a consortium and with Pharma the bods don’t want to know….So much for the “We will be fight them on the beaches” spirit….It’s more “Go online and do some shopping with a cup of tea” spirit. Dr Angry is so angry there is no more blood to spit. OK rant over

ProfG has put up the idea of MS spreaders….people who are immunosuppressed who don’t get rid of COVID-19 virus quick enough. Here is a sugesstion that this occurs.

COVID-19 in a patient with long-term use of glucocorticoids: A study of a familial cluster. Han Y, Jiang M, Xia D, He L, Lv X, Liao X, Meng J. Clin Immunol. 2020 Apr 7:108413. doi: 10.1016/j.clim.2020.108413. [Epub ahead of print]

Clusters of patients with novel coronavirus disease 2019 (COVID-19) have been successively reported globally. Studies show clear person-to-person transmission. The average incubation period is 2-14 days, and mostly 3-7 days. However, in some patients, this period may be longer. Here, we report a familial cluster of COVID-19 where a 47-year-old woman with long-term use of glucocorticoids did not develop any symptoms within the 14-day quarantine period but was confirmed with COVID-19 by tested positive of antibody on day 40 after she left Wuhan. Almost at the same time, her father and sister were diagnosed with COVID-19. The results suggest that the long-term use of glucocorticoids might cause atypical infections, a long incubation period, and extra transmission of COVID-19.

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MouseDoctor

9 comments

  • The COVID-19 spectrum, anything from asymptomatic to ARD and death is shocking. Am trying to think about other novel (emerging) infectious diseases? Maybe West Nile virus. But the mortality due to encephalitis was low.

  • =~\ …. Excellent news. More to worry about.

    Could you not do covid research? Our uni is well up for anyone working as long as the research includes the word covid.

    • On the other hand, ours does not want us to do stuff and is actively stopping us from working on COVID stuff. We could have made the first set of stuff we need to do already and we only needed one person in the lab to start off.

  • MD your too hard on yourself. You for.most part ran this blog single handley and advised MS Community on the science of COVID 19 and how to stay safe. That’s a service not to belittle. Unfortunately if UK didn’t follow in steps of trump and his soundbites we may of had the tests to clear you to go back to work. Besides this is long war and you may still get your chance to go over the trenches.

    • Thanks…Tests is not the reason we can’t go back we are not allowed in the building….unless we are part of a national consortium or have the funding in place. We are now simply planning to put the ideas onto BioRXiv and let some one else do the work if they have a lab they can go to.

      • Agree with Anonymous. Don’t be too hard on yourself, you are doing great work for the MS community. I would suggest coming to ResearchGate to launch a discussion. Happy Easter, I wish that your family is safe.

        • Thanks, and likewise to you stay safe.
          We are writing the protocols for a BioRXiv submission and then maybe research gate could be a good forum, if labs have the interest and the gear and abit of resource then maybe they can finish the paper off, then it may be worth going to research gate.

          • Can’t wait to see it, not sure if I know the right labs with the right kit and skills, but in Australia universities are currently classified as essential activities… all teaching (except limited clinical skills) done online (which is much harder than face to face) but can still get in, and some research still going on (with appropriate social distancing). Happy to help if I can.

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