#MSCOVID19 Breakfast. If you don’t learn from the monkeys you can be a Right Charlie and you have to wash your pants

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The media has got your bowels running scarred again as news filters through of a case of re-infection of COVID-19 virus, 4 months after the first bout. The vaccine won’t work and we are all doomed.

This raises fear that we are going to be stuck indoors for every. However before we stain our pants we have to look at the information.

When this idea first raised its ugly head many months ago people were going back to hospital within a couple of weeks of being discharged with a negative SARS-COV-2 test..The media went off on one and we soiled our pants…doom and gloom. However, it turns out the test is not perfect you can give a negative test when you are still positive and you shed viral fragments from your guts for weeks after it stops going from your nose. However, the test generally just picks but viral fragments and not infective virus. The South Koreans contract traced hundreds of these so called re-infected people and guess what? Not a single person contacted became infected. So you needed to buy some new trousers for no good reason. Alternatively were you going to wash them?

However the media are back at it we have someone with two confimed different strains, we soil ourselves again and destroy our new pants so they have to go online again….now we read the fine print

To et al. COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing, Clinical Infectious Diseases, , ciaa1275, https://doi.org/10.1093/cid/ciaa1275

It says “The second episode of asymptomatic infection occurred 142 days after the first symptomatic episode in an apparently immunocompetent patient. During the second episode, there was serological evidence of elevated C-reactive protein and SARS-CoV-2 IgG seroconversion” So when the person got infected a second time they did not get symptoms…..This is what I call immunity. To think that your immune system can stop you being in contact with the virus again is daft. The point of immunity is that you deal with the infection the second time..the person had no symptoms.

Now take a monkey you infect it the first time round the monkeys get fever and body weight loss as a sign of being unwell and they make virus for 7-10days they get re-infected the next time they have abit of a fever for a day and dont make any virus….They are immune.

It is not rocket science but it is amazing the number of scientists who have made comments and themselves without reading the paper. More washing and you look a right charlie. it could be worst:-)

I am sure there will be cases of re-infection however the question is whether it is going to be the norm like with some cold-causing coronaviruses however, enough immunity to stop SARS-COV-2 from being a killer would be a positive step. As for how the vaccine will fair, I have my views and I wonder if just going the Spike protein is the most sensible thing. Time will tell.

However it seeems that if you had ripp-roaring COVID your antibody response may presist for a good few months, but if the symptoms were not noticable then the antibody response may not develop or it may not persist for more than a few days/weeks. So many people may be immune but have nothing to show for it. The issue may be then will people get bad injection site reactions when the.y eventually get a vaccine

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MouseDoctor

12 comments

  • Perhaps we are also underestimating the ability of T cell based innate immunity to deal with this Sars-Cov2-19 infection. (https://pubmed.ncbi.nlm.nih.gov/32726801/) This asymptomatic case (oxymoron?) tested positive, as you say for viral fragments and IgG so was immune, thus no symptoms.
    Yet, surely something is going on to explain the very low impact of COVID19 in the UK right now. It’s nearly September and the caseload has all but disappeared. Perhaps the new strain is less pathogenic? Will there be a winter wave at all?
    I feel sure that the measures taken in schools, hospitals and on public transport are doing more harm than good.
    And why the big drop in the rate of premature birth during the lockdown? https://www.drbannonsblog.com/2020/08/lockdown-where-have-premature-babies.html

    All very interesting!

  • Love the photo. 😂
    Also some people just have crap immune systems, my sister got full blown chickenpox twice (spots all over, down the throat etc) once when I brought it home from school and then again 4 years later after she had started school. We were both vaccinated for measles but she also managed to get a decent case of measles as well.
    Fortunately her immune system seems to have improved as she got older… she works in early childhood education and seems to escape the multiple colds that circulate regularly.

  • Haha, I didn’t scroll down far enough and put too much thought into why someone would peg their clothes like that before I saw the whole picture!

    Definitely wash them, I can’t afford to keep throwing away clothes, unless I need to justify something new of course. then they couldn’t possibly be salvageable. 🙂

  • Excellent explanation of immunity and Covid-19 thoughts.
    All you hear about is wearing masks, Social distance, huddle inside.
    All I see is People not wearing masks, Grandparents caring for Grandchild so the parents can work. It’s like a virus 🦠 in a blender. Mixing, mixing. Pharma wants a vaccine so badly. Yes, the “T” word is a derogatory slang word in USA. Almost can’t post this because of that but the rest is so informative!

  • Assessment of the risk of SARS-CoV-2 reinfection in an intense re-exposure setting
    Laith J Abu-Raddad et al. medRxiv 2020.08.24.20179457; doi: https://doi.org/10.1101/2020.08.24.20179457

    Background: Reinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a subject of debate. We aimed to assess the risk and incidence rate of documented SARS-CoV-2 reinfection in a large cohort of laboratory-confirmed cases in Qatar.
    Methods: All SARS-CoV-2 laboratory-confirmed cases with at least one PCR positive swab that is ≥45 days after a first positive swab were individually investigated for evidence of reinfection, and classified as showing strong, good, some, or weak/no evidence for reinfection. Risk and incidence rate of reinfection were estimated.
    Results: Out of 133,266 laboratory-confirmed SARS-CoV-2 cases, 243 persons (0.18%) had at least one subsequent positive swab great or equal to 45 days after the first positive swab. Of these, 54 cases (22.2%) had strong or good evidence for reinfection.

    Median time between first and reinfection swab was 64.5 days (range: 45-129).
    Twenty-three of the 54 cases (42.6%) were diagnosed at a health facility suggesting presence of symptoms, while 31 (57.4%) were identified incidentally through random testing campaigns/surveys or contact tracing.

    Only one person was hospitalized at or following time of reinfection swab, but still had relatively mild infection. No deaths were recorded. Risk of reinfection was estimated at 0.04% (95% CI: 0.03-0.05%) and incidence rate of reinfection was estimated at 1.09 (95% CI: 0.84-1.42) per 10,000 person-weeks.

    Conclusions: SARS-CoV-2 reinfection appears to be a rare phenomenon suggestive of a strong protective immunity against reinfection that lasts for at least a few months post primary infection.

    • Risk for documented reinfection was rare at only 4
      reinfections per 10,000 infected persons. This finding is striking as the epidemic in Qatar has been intense with half of the population estimated to have been infected

      None were severe, critical, or fatal, all reinfections were asymptomatic or with minimal or mild symptoms. These findings suggest that most infected persons do develop immunity against reinfection that lasts for at least few months, and that reinfections (if they occur) are well tolerated and no more symptomatic than primary infections.

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