ArchiveDecember 2020

#MSCOVID19 Protection: Reasons for Vaccination

Having an antibody response is associated with protection from re infection Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Lumley SF et al. N Eng J Med DOI: 10.1056/NEJMoa2034545 BACKGROUND: The relationship between the presence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the risk of subsequent reinfection remains unclear. METHODS: We...

The Oxford vaccine…I mean COVID-19 vaccine zeneca

Want a read The Oxford University/AstraZeneca vaccine has been approved for use for people 18 years or older and consists of two doses, with the second dose administered 4-12 weeks after the first dose. The transportation and storage requirements for this vaccine mean that it needs to be kept at temperatures of 2C to 8C, which is similar to a conventional fridge for up to six months and can be...

Blurb about COVID-19 Vaccines from UK Government

If you want to read about the two approved vaccines in the UK. They have not tested people taking immunomodulatory agents and are covering themselves by saying that they may not work totally effectively. This is why we need to collect the data UK Public UK Public Pfizer BioNTech It says “Talk to your doctor, pharmacist or nurse before you are given the vaccine if you have: a weakened immune...

Bed to 5km Challenge

It’s officially over! Prof G and Dr Ruth, paired-up this afternoon for a socially-distanced 5-km walk around Brockwell Park in South London. This officially completes Prof G’s ‘Bed to 5-km Challenge’ to help raise money for Dr Ruth’s and Dr Angray’s COVID-19 antibody study. The good news is that the Barts-MS team through ‘Prof G’s virtual NYC...

BartsMS COVID-19 vaccine advice

Following on from ProfG’s vaccine-post yesterday, I’ve now uploaded the vaccine advice BartsMS have produced for pwMS. As always with such documents, it is going to age rather quickly as new evidence emerges. COVID-vaccine-guidance-in-MS_final_1.3 I support ProfG’s view 100% that you should have the vaccine, unless there are specific contra-indications. I also agree that...

Food for thought

The gastrointestinal tract (image taken from The Conversation) You may not think much of your gut, which in most peoples mind is simply one giant hosepipe from start to finish. But, this week after eating something quite oily, I was painfully made aware of my gut’s existence. The gut from an energy and metabolic point of view is a very important organ, and without it you would simply be a...

#MSCOVID19: yes, have the vaccine

Barts-MS rose-tinted-odometer: ★★★★★ Despite the long blog post that I called CATCH-22 I am still getting numerous emails and questions from patients with MS about whether or not they should have a COVID-19 vaccine. YES, you should have the vaccine when it is offered to you. Clearly, timely access to the vaccine will depend on where you live, how vulnerable you are and the local, regional and...

Variations in neurofilament

Neurofilament is fast becoming a new biomarker for MS, but ths research suggests that there is variant form one time point to another. Variations in consecutive serum neurofilament light levels in healthy controls and multiple sclerosis patients.Bridel C, Verberk IMW, Heijst JJA, Killestein J, Teunissen CE.Mult Scler Relat Disord. 2020 ;47:102666 Background Neurofilament light is a neuronal...

A leopard can’t change its spots or is it just common sense

Biological Significance of Anti–SARS-CoV-2 AntibodiesLessons Learned From Progressive Multifocal Leukoencephalopathy Navid Manouchehri, Lawrence Steinman, Olaf Stuve. Neuology N2. DOI: Objective To discuss the pathogenic and diagnostic relevance of cellular and humoral immune responses against severe acute respiratory syndrome novel coronavirus (SARS-COV-2) and...

Unsteadiness

Barts-MS rose-tinted-odometer: ★★★★★ How many of you people who have MS (pwMS) have balance problems; i.e. when you stand and close your eyes or try and stand on one leg you tend to fall?  Since my accident, I have been having problems with balance. I first noticed it when I tried to stand on one leg and I would feel unsteady. When walking to and from the bathroom at night I tend to veer to one...

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