I thought I would have a look to see what the information says about fever after the Jab. This may be important to you as temperature can transiently worsen some peoples signs if there are demyelinated lesions. This can mean a transient increase in signs due to Uthoffs phenomenon
I thought I could try and decipher what happens from the papers, but the best source of data if from the regulatory approval rather than the papers. The FDA is a good source of information
In the UK, we currently have the Pfizer, Moderna and Astrazeneca vaccines approved, in the EU there is the Pfizer, Moderna amd Astrazeneca (although they dont seem to be using in it in older people) vaccine and in the US there is the Pfizer/BioNTech, Moderna and Janssen vaccines approved.
As I have said a number of times the Oxford trials have been a bit of a “dogs breakfast” in their application as they were doing studies without access to the vaccine meaning the dose and the dose intervals were all over the place. I was surprised to see that in the regulatory documents from the MHRA (UK) and EMA (EU) there is not much data given that thousands of people have been treated in the trials. There is no data for fever after the first and second dose, although this can be found in a study of very few people. It simply says the occurrence of fever was 7.9%. One images this was based on thousands of points. But it is is not clear.
This document lacks some clarity that can be found in the FDA documents and makes you think this is one of the reasons that the Astrazeneca vaccine has not yet been approved in the USA and as time is passing you wonder whether it will ever be approved and used in the USA. I believe a trial is being done and apparently it may be finshed in a few weeks so. But it is behind the curve and maybe it they don’t want it they can send some over here, or the EU for the Whipper snappers or maybe to a country that needs it:-).
It is hard to compare the different agents, they were do on differnt people, different age groups and are reported in different ways. Generally older people do not react as badly as the younger people so for the US readers, I have fished out the data relating to the development of fever, equal to or more than 38 degrees centigrade, in old money that is 100 degrees Fahrenheit. I have grouped the old together and class severe fever above 39 degrees centrigrade
The occurrence of fever is in bold
There are many similarities. It is clear from the RNA vaccines that Fever is more common on the second dose, there is only a small study reported that suggests for the Astrazeneca vaccine the reactions may be less second time round.
As some people have said the effects of vaccine fever are going to be more transient than COVID-19 fever. Fever from COVID-19 occurs in about 50% of mild and asymptomatic individuals according to the European CDC. Therefore, the vaccine is better than getting COVID-19.