I have to give a disclaimer that I have just made this up!…….No, I didn’t work for the BCC:-), but it could be a possibility that after drinking: Lip-smacking, ace-tasting, motivting, good, buzzing-cool, walking-high, living, evergiving, cool fizzing……pop…….yep I don’t want to say anything specific, in case I get sued for linking anything to relapsing MS. How do you prove it?…..You can’t. However if everyone that drinks fizzy pop with MS got a relapse in a few days, I might believe it.
Tumefactive Demyelinating Lesions in a Patient with Multiple Sclerosis Developed two Days after the Injection of Rituximab
Background: Rituximab has been increasingly prescribed in the treatment of multiple sclerosis (MS) over recent years. Tumefactive demyelinating lesions can occur at the onset or over the course of MS. Another major cause of these lesions is the side effects of drugs such as natalizumab or fingolimod. This study is a case report of a young MS patient who suffered from tumefactive lesions following the injection of rituximab.
Case presentation: The patient was an 18-year-old man with MS who developed double vision, imbalance, and quadriparesis symptoms followed by a decrease in his consciousness two days after administration of rituximab. Tumefactive lesions were observed in the patient’s brain magnetic resonance imaging (MRI).
Conclusion: Rituximab should be considered as a potential cause of tumefactive demyelinating lesions in patients with MS.
So here we have an observation but we know from the fact that there are thousands of people with MS that have taken rituximab that have not had tumefactive (MS lesions that look like tumours) MS that is it is not a generalised phenomenon…..However, I remember being in Greece once and a Neuro asked be about disease activation after CD20 depletion. Have you had such an experience?
Disclaimer: Please note that the opinions expressed here are those of author and do not necessarily reflect the position of the Barts and The London School of Medicine and Dentistry nor Barts Health NHS Trust.