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MouseDoctor

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  • Not by a drug! It is friction causing MRI image. Cerebellum is rubbing a healed up External Occipital Crest, meaning friction point. The MRI image is rubbing between them. The damage happened as a kid. I know this because I’ve lived it, MD.

  • Prof G was advocating for early highly effective treatment 20 years ago and the wider neurology field is just now coming around to his point of view (and even then, they still think anti-CD20 is the answer). The idea of curing MS will probably take just as long to gain acceptance 🙁

    • Only when the dinosaurs are long gone, sadly. There are still too many of them left and in positions of influence.

      • Even this is questionable as the young ones have the same ( even “better”) incentives to use the same weapons to deal with the ms

        • Yes, there is a large element of truth in that and they will have learned from the dinosaurs.

  • I only know a few neurologist but, my guess is most of them got there head up there … Will take good criteria and biomarkers to move the stubborn one’s. Side effects might be no joke but, if you’re getting agressive MS it will take everything from you.

  • What do you think on valganciclovir which acts against HHV6 and EBV? Would it be good as a stand alone therapy or in combination?

  • Thanks so much for the share!
    My name is Bram Platel, a Dutch MS patient. I have a Ph.D. in biomedical engineering, and I am the founder and director of a Dutch non-profit foundation called ‘Stichting MS in beeld.’
    We felt that many people with MS had many questions that their neurologist didn’t have time to explain in detail. Scientific papers were often too difficult to understand.
    Therefore we set our goal to help people with MS by communicating scientific insights in an accessible but in-depth manner.
    For example, last year, we made lots of videos about MS and COVID-19 and the vaccine. We also have videos about the MRI scanner and the images it makes and a detailed series about lumbar punctures in MS.
    http://www.msinbeeld.nl/youtube
    Up to now, our videos have all been in Dutch. The last three videos I uploaded are in English with Dutch and English subtitles.
    I hope to help more than just the Dutch MS patients with our videos by making these English spoken videos.
    However, I don’t yet have a good way of reaching the rest of the world with these English videos.
    ⁠Any ideas about how we can reach more people with these videos are more than welcome!
    I believe that they can help many others with MS.

  • Ok good video but how are the treated young doing by now? Surely some years have past where is the data?

  • Mr. Platel’s video works very well and makes the whole mess quite a bit easier to understand and refer to. I’ve been with this whole mess since before the 1st DMT came out in 1994, and it wasn’t long after that the “early treatment mantra” began. So I am always surprised now, today, when I see a new article on some MS website, stating that early treatment may delay or prevent disability. It should be the first thing an MSr is presented with. I think the data is there to answer the question, I’ve seen a few reports, but I would imagine the confounding variables to weed out the effect are sometimes hard to overcome.

    My biggest question regarding this video, and perhaps Mr. Platel can think about visualizing this, is how does smoldering MS fit into this? I’m talking about NEDA with no evidence, clinical or MRI, of disease activity. Or more fundamental to this, is- is “it” or is “it” not, new disease activity or are we just talking about smoldering MS is loss of reserve? Second to this, is increasing reserve possible? I’m not talking about doing things to prevent a decrease in reserve, but to actually increase it? I wonder if all those “balance” things I did as a kid, like playing on the bongo board, trying to surf, skiing, riding a bike with no hands, etc., increased my “balance reserve” at an earlier age? Food for thought…

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