This was a debate I fought yesterday in Gods own Country……. and I am still in shock that I lost:-(.
As I pointed out all effective therapies (eg alemtuzumab,caladribine, ocrelizumab, interferons etc.) for MS depleted B cells and stop them entering the CNS and supplied fact. The opposition seems to use the “Chewbacca defence” and cited nothing relevant to the debate but just like Chef defend by Johney Cochrane in South Park..they won:-)
I wonder whether COVID-19 and CD20 sunk me with regard the “SAFEST” if they had used SAFE I may have Won:-
As I was off to the toilet to slash my wrists….an audience member said it was interesting how a scientist and a clinicican approaches the contest. Maybe I did information overload.
Maybe the arguments used were just rubbish
However, next week we may be able to post on how to make CD20 safer during COVID-19 Dr Ruth has submitted the paper if may surface soon.
My opponent used COVID-19, dubious information and some case histories where most people may select natalizumab or cladribine, HSCT as choices…..They would not accept that natalizumab cladribine and HSCT are B cell depleting therapies. In these debates you just have to create some doubt. However it tries to provide balanced information with a YES and NO argument
General Disclaimer: Please note that the opinions expressed here are those of the author and do not necessarily reflect the positions of the Barts and The London School of Medicine and Dentistry nor Barts Health NHS Trust and are not meant to be interpreted as personal clinical advice.