Bateman GA, Lechner-Scott J, Carey MF, Bateman AR, Lea RA. Does the venous pressure theory of multiple sclerosis pathophysiology deserve a second chance? Mult Scler Relat Disord. 2021 Sep 13;56:103262. doi: 10.1016/j.msard.2021.103262.
The theory that multiple sclerosis is related to venous pressure has been discredited due to previous operator dependent diagnostic criteria and premature attempts at treatment. (1) An elevation in venous pressure may only be a component of the compliance changes found in MS. (2) The neck veins may only supply a component of the venous pressure elevation found intracranially. Although a more targeted approach towards neck angioplasty (both towards disease subtype and those with more favorable stenoses) may be beneficial, we would advocate caution. We encourage others to give the venous pressure theory a second chance and to replicate our work.
Where is Nancy Reagan when you want her to say something…Just say…..
Replicate this stuff before Canada throws another few million:-)