Every now and then we get an unusual paper that draws me like a magnet. If you have a few million squid to blow….you may be considering lining the pockets of Elon Musk or Sir Richard Branson for a trip into space….but as you go weight-less, I guess you are pondering what does space do to your oligodendrocytes….Fear not someone has been looking at this….and you can read it, if interested…..
Tran V, Carpo N, Shaka S, Zamudio J, Choi S, Cepeda C, Espinosa-Jeffrey A. Delayed Maturation of Oligodendrocyte Progenitors by Microgravity: Implications for Multiple Sclerosis and Space Flight. Life. 2022; 12:797
In previous studies, we examined the effects of space microgravity on human neural stem cells. To date, there are no studies on a different type of cell that is critical for myelination and electrical signals transmission, oligodendrocyte progenitors (OLPs). The purpose of the present study was to examine the behavior of space-flown OLPs (SPC-OLPs) as they were adapting to Earth’s gravity…….We conclude that microgravity is becoming a novel platform to study why in some myelin disorders OLPs are present but do not mature.