AuthorArie Gafson

Natural History Studies

This is a retrospective study using the MS Registry in Kuwait. They took a cohort of patients and looked at certain variables to see if they were predictive of MS progression. The study is not revolutionary in its findings – it shows that a late age of onset, male gender and relapse frequency are all poor prognostic markers and increase the risk of progression to secondary-progressive MS...

Predicting your MS trajectory using a personalised approached

This study takes an evidence-based approach to making a personalised predictive tool for MSers. The aim is to be able to predict your chances of converting from CIS (clinically isolated syndrome) to CDMS (clinically-definite MS), RRMS (relapsing-remitting MS) to SPMS (secondary progressive MS) and your predicted level of disability at 10 and 20 years from diagnosis.  The author states that...

Long-term effect of Copaxone

This retrospective cohort study from Spain aims to analyse the long term outcomes of patients on Copaxone.  The main headline findings are the following 85% of patients remained free from disability progression (as measured by EDSS) Stable EDSS over the study period (i.e. no significant change from the beginning to the end of the period) Reduction in annual relapse rate  Reduction in T1...

MS Role Models Take 2

Despite the mixed reception on my previous post on MS Role Models I’m going to brave the storm and talk about another inspiring MSer – Ann Romney. Ann Romney is the wife of Mitt Romney the Republican nominee in the 2012 US Presidential election. Wherever your political leanings lie, try to stay with me!  Ann Romney was diagnosed with relapsitting-remitting MS in 1998...

Mindless Neurology and Brainless Psychiatry

How much do your MS symptoms overlap between the realms of neurology and psychiatry? Is there really a difference between the two? The pioneers of neuroscience moved freely between neurology, neuropathology, psychiatry and psychology. Charcot who first described MS as ‘sclerose en plaques’ was first and foremost interested in  hysteria; classically a psychiatric symptom. The two...

MS Role Models

I can’t help but feel that their is an air of pessimism on the blog this week – centred mainly around Prof G’s post on Cognitive MS – where he tried to raise awareness of this issue and to emphasise that MS is a ‘preventable dementia’. His reason for this is simple; if he can persuade the ‘powers that be’ to treat aggressively from early on in the...

All Hail The MS Specialist Nurse

This letter in Multiple Sclerosis Journal highlights the importance of the MS Nurse Specialist in caring for MSers and more specifically in avoiding emergency admissions. The authors looked at hospital emergency admissions in MSers before and after a cash injection which boosted Nurse Specialists hours. The authors claim that there was a reduction in hospital bed usage from 2700 bed days per year...

Increased risk of bipolar disorder and depression in MSers.

This is an interesting study conducted using the Swedish National Patient Register looking at the risk of developing MS in patients with psychiatric disorders. The paper showed that patients with depression and bipolar disorder are more likely to develop MS but that patients with schizophrenia are less likely to develop MS. This study has a number of advantages over similar studies conducted in...

An Interesting first presentation of MS

This case report outlines an interesting first presentation of MS in a 28 year old man.   The levels of water in your bloodstream are maintained at the right level by a process called homeostasis and more specifically by a hormone called antidiuretic hormone (ADH). Diuresis is the process of passing urine so the hormone does exactly what it says in the tin – it stops you peeing. ADH is...

Spotlight on ECTRIMS – A junior doctor perspective.

I wrote this satirical piece following my experiences of ECTRIMS last year – hope you enjoy! In early October of this year, I was fortunate enough to attend the 29th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) and the 18th Annual Conference of Rehabilitation in MS (RIMS) in Copenhagen, Denmark. During my final year at medical school, I...

Translate

Categories

Recent Posts

Recent Comments

Archives