E-pub: Cramer et al. Yoga for Multiple Sclerosis: A Systematic Review and Meta-Analysis. PLoS One. 2014 Nov 12;9(11):e112414. While yoga seems to be effective in a number of neuropsychiatric disorders, the evidence of efficacy in multiple sclerosis remains unclear. The aim of this review was to systematically assess and meta-analyze the available data on efficacy and safety of yoga in patients...
Yoga for neurogenic bladder dysfunction
Patil et al. Effect of integrated Yoga on neurogenic bladder dysfunction in patients with multiple sclerosis-A prospective observational case series. Complement Ther Med. 2012 Dec;20(6):424-30. BACKGROUND: Neurogenic bladder dysfunction (NBD) is a common distressful symptom in multiple sclerosis (MS) affecting quality of life. Yoga has been widely used in treating various symptoms of...
Research: New white blood cells after Tysabri
Zanotti C, Chiarini M, Serana F, Sottini A, Garrafa E, Torri F, Caimi L, Rasia S, Capra R, Imberti L. Peripheral accumulation of newly produced T and B lymphocytes in natalizumab-treated multiplesclerosis patients. Clin Immunol. 2012;145:19-26. [Epub ahead of print] The anti-α4 monoclonal antibody natalizumab inhibits lymphocyte extravasation into the central nervous system and increases...
Research: More bones
Kirbas A, Kirbas S, Anlar O, Turkyilmaz AK, Cure MC, Efe H. Investigation of the relationship between vitamin D and bone mineral density in newly diagnosed multiple sclerosis. Acta Neurol Belg. 2012 Aug 16. [Epub ahead of print] The aim of this study was to investigate the relationship between vitamin D and bone mineral density in newly diagnosed multiple sclerosis (MS) and to compare results...
Research: Sleep apnea
Braley TJ, Segal BM, Chervin RD. Sleep-disordered breathing in multiple sclerosis. Neurology. 2012 Aug 15. [Epub ahead of print] BACKGROUND:The objectives of this cross-sectional study were to assess the prevalence and severity of sleep apnea in patients with multiple sclerosis (MS)referred for overnight polysomnography (PSG) and to explore the radiographic and clinical features that might...
Bone fractures in MSers
Bazelier MT, van Staa TP, Uitdehaag BM, Cooper C, Leufkens HG, Vestergaard P, Bentzen J, de Vries F. A simple score for estimating the long-term risk of fracture in patients with multiple sclerosis. Neurology. 2012 Aug 15. [Epub ahead of print] OBJECTIVE: To derive a simple score for estimating the long-term risk of osteoporotic and hip fracture in individual patients with MS. METHODS: Using the...
Incontinence and not only
Tubaro et al. The Treatment of Lower Urinary Tract Symptoms in Patients With Multiple Sclerosis: A Systematic Review. Curr Urol Rep. 2012 Aug 12. This is a systematic review on the treatment of lower urinary tract symptoms (LUTS) in patients with multiple sclerosis (MS). The heterogeneity of the outcome criteria did not allow a meta-analysis of the published evidence. In the last few...
Research: Imaging disability
Harrison DM, Shiee N, Bazin PL, Newsome SD, Ratchford JN, Pham D, Calabresi PA, Reich DS. Tract-specific quantitative MRI better correlates with disability than conventional MRI in multiple sclerosis. J Neurol. 2012 Aug 12. [Epub ahead of print] Although diffusion tensor imaging (DTI) and the magnetization transfer ratio (MTR) have been extensively studied in multiple sclerosis (MS), it is still...
Research: Action of Mitoxantrone
Burns SA, Lee Archer R, Chavis JA, Tull CA, Hensley LL, Drew PD. Mitoxantrone repression of astrocyte activation: Relevance to multiple sclerosis. Brain Res. 2012 Aug 2. [Epub ahead of print] Mitoxantrone has been approved by the FDA for the treatment of multiple sclerosis (MS). However, the mechanisms by which mitoxantrone modulates MS are largely unknown. Activated astrocytes produce nitric...
Research: Controlling microglia
Starossom SC, Mascanfroni ID, Imitola J, Cao L, Raddassi K, Hernandez SF, Bassil R, Croci DO, Cerliani JP, Delacour D, Wang Y, Elyaman W, Khoury SJ, Rabinovich GA. Galectin-1 Deactivates Classically Activated Microglia and Protects from Inflammation-Induced Neurodegeneration. Immunity. 2012 Aug 8. [Epub ahead of print] Inflammation-mediated neurodegeneration occurs in the acute and the chronic...