AuthorMark Baker

Education PNS and CNS axons

Peripheral nervous system and central nervous system nerve axons Mark Baker tells you more about nerves A nerve that we see in the peripheral nervous system (PNS) or a white-matter ‘tract’ in the central nervous system (CNS) is composed of many axons. The axons are elongated extensions of individual nerve cells, and they are structures specialized for signalling over distance. Let me try to...

Education: What is a nerve impulse?

What is a nerve impulse? How does a nerve axon generate it and allow signalling using impulses from one place to another? The impulse may be thought of as a message or wave.  A ‘message’, for example on a telegraph, or a ‘wave’ in the sea initiates at one point and ends up elsewhere. The message needs the medium: the wave may have travelled great distances, but it cannot exist without the...

Temperature dependence of impulse conduction in optic nerve axons

Thanks for the comments We were grateful when a number of readers responded to our enquiry regarding temperature dependent symptoms in MS, and we learned more about how people cope with the symptoms. Following this conversation, I thought it worthwhile to draw attention to a paper we recently published, that suggests that there are functional differences between normal peripheral and central...

Temperature

Twists and turns in the MS research trails Hi, I am Mark Baker, a university lecturer, and I teach neuroscience to medical and science students at QMUL. I am also a member of Barts MS and have maintained an interest in MS over many years. I have been involved in research investigating the mechanisms of excitability in normal and diseased nerve, involved in pain signalling and the effects of...

Temperature sensitivity of CNS axons

Temperature sensitivity of central axons Tom A. Coates, Oscar Woolnough, Joseph M. Masters, Gulsum Asadova, Charmilie Chandrakumar & Mark D. Baker (2015) Acutetemperature sensitivity in optic nerve axons explained by an electrogenicmembrane potential PflügersArchiv European Journal of Physiology (DOI) 10.1007/s00424-015-1696-2 Classical work in squid axon reports resting membrane potential is...

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