AuthorProf G

Professor of Neurology, Barts & The London. MS & Preventive Neurology thinker, blogger, runner, vegetable gardener, husband, father, cook and wine & food lover.

#MSCOVID19: Asymptomatic Shedders

Barts-MS rose-tinted-odometer: ★ The reason why so many people are coming down with COVID-19 and the second-surge is truly surging is the observation that three-quarters of people who are actively shedding SARS-CoV-2, i.e. have positive tests, are asymptomatic at the time of testing (see the latest study below). In summary, having symptoms suggestive of COVID-19 is a very poor marker of whether...

#DietSpeak: saturated fats – challenging the dogma

Barts-MS rose-tinted-odometer: ★★★ Since my rather neutral “#DIETSPEAK: IS THERE AN IDEAL MS DIET?” post last week, in which I refuse to support any particular MS diet I have had a  torrent of social media abuse about my position. Intriguingly, many people out there have bought into the falsehood that saturated fats are bad for you and some commentators even believe that saturated fats cause MS...

#MSCOVID19: anti-CD20 nuances

Barts-MS rose-tinted-odometer: ★★★ I had to have a detailed discussion with a patient this week about starting ocrelizumab during the COVID-19 pandemic. This patient was concerned about (1) the data showing an increased risk of COVID-19 in anti-CD20 treated patients, (2) an increasing number of cases not seroconverting when being infected with the coronavirus and (3) she will not be able to have...

#MSCOVID19: need to fly?

Barts-MS rose-tinted-odometer: ★★ The following is some sound, sensible, advice about how to reduce your risk of being exposed to coronavirus on an aeroplane. Image from JAMA Pombal et al. Risk of COVID-19 During Air Travel. JAMA. Published online October 1, 2020. doi:10.1001/jama.2020.19108Wear a mask, don’t travel if you feel unwell, and limit carry-on baggage. Keep distance from others...

#DietSpeak: is there an ideal MS diet?

Barts-MS rose-tinted-odometer: ★★★★★ I am always being asked about what is the ideal diet for someone with MS. The simple answer is there is no ideal MS diet. What you eat is about personal choices and has to be compatible with your cultural background and your social circumstances. There is so much more to eating food than what you actually eat. I have written a piece on Medium called ‘Diet as a...

#MSCOVID19: dropping dead

Barts-MS rose-tinted-odometer: ★★★★★ “Did you hear that Professor Giovannoni dropped dead after attempting to complete the virtual New York Marathon trying to raise money for a multiple sclerosis research project?”  “Prog G finally throws in the towel and arranges to see an orthopaedic surgeon about his failing right hip. His attempt to complete a marathon to raise money for MS research was one...

#MSCOVID19 & education: changing the way we manage MS one young brain at a time

Barts-MS rose-tinted-odometer: ★★★★★ At Barts-MS we spend a lot of time teaching people about MS. It is not only important to generate new information (ideas, testable hypotheses and research), but also to disseminate knowledge (teaching). However, with the COVID-19 pandemic and the resultant social distancing, almost all teaching has gone online and that does not make for very engaging and...

#MSCOVID19: digital health – what will survive?

Barts-MS rose-tinted-odometer: ★★★ I am doing a webinar with Professor Tjalf Ziemssen, a good friend and colleague from Dresden, Germany, this afternoon on the digital management of MS. Interestingly, many of the changes and innovations we have put in place to manage MS during the COVID-19 pandemic will survive and actually thrive in the new NHS, simply because we are a socialist healthcare...

#MSCOVID19: good news

Barts-MS rose-tinted-odometer: ★★★★★ The late late-breaking session at the MSVirtual2020 meeting, which covered COVID-19 has already received a lot of air-time on social media. The big-data alliance confirmed the Italian data, i.e. that people with MS (pwMS) on anti-CD20 are at higher risk of getting COVID-19 and severe COVID-19 (hospitalisation, intensive care admission and/or ventilation)...

#MSCOVID19: Interferon-beta and NABs

Barts-MS rose-tinted-odometer: ★ It is always nice to see evidence supporting a hypothesis you had more than a decade ago see daylight.  If you are on interferon-beta or have been on interferon-beta in the past this post is important to you. It is clear type 1 interferons, such as interferon-beta and alpha, are important antiviral cytokines and are critical in the body’s fight against...

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