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Your questions answered: The impact of hormones, sex and gender on MS

As a follow up from my previous post on ‘Why is MS more common in women?‘ I thought I’d respond to some of your comments and questions… As discussed in the previous post, MS is almost 3 times more common in women compared to men and we came to the conclusion that there is a hormonal link, but this may not be the whole reason for the difference between the sexes. It should...

Why is MS more common in women?

Last month, I attended ‘MS At the Limits’, and the final talk by Dr Riley Bove (University of California, San Francisco) was truly fascinating. I know I am a bit delayed in posting this but I thought I would share some of the key points… As most of us know, MS affects more women than men, but you might not know that women tend to have more relapses and that the ratio of men:women affected by MS...

Translocator protein: useful to see, useful to target?

Translocator protein (TSPO) is found on the outer mitochondrial membrane (in other words, on the outside of the powerhouse of the cell). It is thought to be involved in regulation of several cellular processes but its actual function is still up for debate.  TSPO became of interest because it is associated with activation of microglia (the immune cells of the brain). It was found that this...

MS in the news today

You may have seen this BBC news article today about two pwMS. One of which had a well-planned trip to Switzerland to end his life. After meeting a local woman with MS he appears to have a new outlook and has postponed his trip to Switzerland indefinitely. (Image is a screen shot of the article on the BBC website) The really interesting thing here is that the main way in which the woman has...

Introducing MouseDoctor3

Hello, and thank you for reading my first post as MouseDoctor3.  Here’s a brief introduction so you know my background… Name: Dr Jodie Stephenson Role: postdoctoral research assistant Bosses: MouseDoctor and Dr Love Location: primarily the Blizard Institute, QMUL, but also Imperial College London and VU University of Amsterdam (i.e. I get to travel around a lot). Project...

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