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Menopause and MS

Impact of natural menopause on multiple sclerosis: a multicentre study. Baroncini D, Annovazzi PO, De Rossi N, Mallucci G, Torri Clerici V, Tonietti S, Mantero V, Ferrò MT, Messina MJ, Barcella V, La Mantia L, Ronzoni M, Barrilà C, Clerici R, Susani EL, Fusco ML, Chiveri L, Abate L, Ferraro O, Capra R, Colombo E, Confalonieri P, Zaffaroni M. J Neurol Neurosurg Psychiatry. 2019. pii: jnnp-2019...

Street Light Science in EAE…

What’s Street light science? Central nervous system targeted autoimmunity causes regional atrophy: a 9.4T MRI study of the EAE mouse model of Multiple Sclerosis. Hamilton AM, Forkert ND, Yang R, Wu Y, Rogers JA, Yong VW, Dunn JF. Sci Rep. 2019; 9(1):8488. doi: 10.1038/s41598-019-44682-6 Atrophy has become a clinically relevant marker of progressive neurodegeneration in multiple...

Scotland-MS Central

BACKGROUND: Fifteen regional studies published over the last six decades surveying prevalence, mortality and hospital admissions have suggested that Scotland is amongst the highest risk nations for multiple sclerosis (MS) in the world. However, substantial intranational variation in rates (between regions) has been described in numerous countries, including in the only previous Scottish...

MS Frontiers

Every alternate year we have the MS Frontiers sandwiched between MS Life organized by the Multiple Sclerosis Society. MS Frontiers is for HealthCare Professionals and MS Life is for people with MS. The 3 Ps of MS Frontiers 2019 As an early career researcher or health care professional, few things are more enriching than the chance to meet leaders in the field, to learn from them, be inspired by...

Teriflunomide long-term effects…You can’t have it both ways

Characterizing lymphocyte counts and infection rates with long-term teriflunomide treatment: Pooled analysis of clinical trials. Comi G, Miller AE, Benamor M, Truffinet P, Poole EM, Freedman MS. Mult Scler. 2019 Jun 7:1352458519851981. doi: 10.1177/1352458519851981. [Epub ahead of print] BACKGROUND:In Phase 3 studies, teriflunomide reduced relapse rates and disability progression compared with...

MS and Electric Devices

Relationship between the use of electronic devices and susceptibility to multiple sclerosis. Khaki-Khatibi F, Nourazarian A, Ahmadi F, Farhoudi M, Savadi-Oskouei D, Pourostadi M, Asgharzadeh M. Cogn Neurodyn. 2019 Jun;13(3):287-292 Multiple sclerosis (MS) is an autoimmune condition influenced by both genetic and environmental factors. Dirty electricity generated by electronic equipment is...

Pregnancy and MS

Pregnancy and Family Planning in Multiple Sclerosis. Langer-Gould AM.Continuum (Minneap Minn). 2019 Jun;25(3):773-792 PURPOSE OF REVIEW: This article provides practical guidance on successful management of women with multiple sclerosis (MS) through pregnancy and the postpartum period. RECENT FINDINGS: Recent studies indicate that most women diagnosed with MS today can have children, breast-feed...

More microbiome ceasarian sections and milk affect MS onset

Caesarean section and infant formula feeding are associated with an earlier age of onset of multiple sclerosis. Dalla Costa G, Romeo M, Esposito F, Sangalli F, Colombo B, Radaelli M, Moiola L, Comi G, Martinelli V. Mult Scler Relat Disord. 2019;33:75-77 Mode of delivery and lactation are among the earliest factors influencing gut microbiota composition and potentially MS risk, but their...

Oligoclonal bands…here to stay

J Neuroimmunol. 2019 May 16;333:576966. doi: 10.1016/j.jneuroim.2019.576966. [Epub ahead of print] Persistence of intrathecal oligoclonal B cells and IgG in multiple sclerosis. Tomescu-Baciu A, Johansen JN, Holmøy T, Greiff V, Stensland M, de Souza GA, Vartdal F, Lossius A. Abstract In multiple sclerosis (MS), B cells are trafficking across the blood-brain barrier, but it is not known...

Reproductictive choices

Reproductive history of the Danish multiple sclerosis population: A register-based study. Moberg JY, Laursen B, Thygesen LC, Magyari M. Mult Scler. 2019 May 30:1352458519851245.  BACKGROUND: A diagnosis of multiple sclerosis (MS) may impact the choice of parenthood. OBJECTIVE: To investigate the number of live births, abortions and ectopic pregnancies among persons with MS. METHODS: From the...

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