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Optic neuritis as an early sign of Multiple Sclerosis

The occurrence of optic neuritis (ON, visual loss) over a persons lifetime is quoted as 50%, however the occurrence of ON as the first manifestation of MS is only 20%. If you’re not careful this can lead to misdiagnosis. Having ways of predicting those at a greater risk of going onto developing MS is therefore key. Many have looked at this in the past and this the latest iteration of it...

Education. Whats an MRI

A BRIEF BEGINNER’S GUIDE TO THE BRAIN AND MRI Thanks to MS Society for this one This a re-post but many of the readers wont have seen this before and it was one of the most popular posts. I will be digging stuff from the archive The brain The brain has three main parts: the cerebrum, the cerebellum and the brain stem. The cerebrum is the big part on the top which most people think of as the...

Can we optimize CD20 for COVID protection?

The answer one suggests is Yes but will it happen? I don’t know. Or should I say I don’t know how much it will occur in the UK. It is a rapidly changing environment Here are two papers one with alot of references and speculation galore (Long hand)  and one with the data without to much commentary (short hand) for you to decide. Also looking at the data from a what causes MS sort of...

Public Engagement is recognised

Although the MSblog is not a Queen Mary University of London website, you may be interested to hear that Queen Mary University of London has become the first university to be awarded the Platinum-level Engage Watermark in recognition of its sector-leading support for public engagement and commitment to excellence. This is the first award of its kind in the UK and attests to the University’s...

MS DMT Is your option going to be….anti-virals?….What’s happening with the imods?

I realise many of you are sick of the COVID-19 stuff, but it continues to come. We are now up to 210,000 COVID-19 papers and counting, which is twice th total MS literature. Believe it on not, early-on I was reading every paper every day, so I could understand what was going on and what was likely to happen to you, so I could pass that on to the clinical team in the front line. A thousand papers...

Do antibody levels influence COVID infection in MS?

Impact of mass vaccination on SARS-CoV-2 infections among the total multiple sclerosis population receiving immunomodulatory disease-modifying therapies in England Nikos Evangelou, Afagh Garjani, Sameer Patel, Dhiren Bharkhada, Waqar Rashid, Alasdair Coles, Graham Law Research Squared Doi: 10.21203/rs.3.rs-1016584/v1 This study aimed to understand changes in the risk of SARS-CoV-2 infection among...

Here we go again – the latest COVID-19 advice from BartsMS

We are all aware this Blog has been deep cleaned from anything related to BartsMS, but hey here I am, as are NeuroDoc Gnanapavan with her fanbase, MD and his significant following, and then are Dr Smets, BartsMS doctor at large, and the more sporadic posters such as AdamsAcademic DrBenJ, and if you haven’t heard about his project I suggest you check here. So, BartsMS is alive and kicking...

Is your mind ready for a derisky business?

Over the past years, anti-CD20 treatments such as Ocrevus have quickly superseded other DMTs on the first and second line treatment shelf. This is good news, because Ocrevus has a high efficacy in controlling MS-related inflammation. The MRI results are very impressive, and pwMS treated early with this drug will definitely do better in the long run. However, the most logical outcome of solving...

COVID-19 The Eye of the Storm. Should the immunosuppressed take the blame?

This is not directly related to MS so read if intested dont if you are not interested I was teaching on friday and got a meal voucher for the Cafe…so I went in to get a few cans of pop for ProfK and was amazed to see all the perspex shielding that stops the Cafe staff from being breathed upon, have been removed. I went out to do a face to face exam and I had to do a risk assessment to...

Shout Out..Get Ebaying

AnnonieMouse is a regular on the blog and has been regressing to someones childhood and is having a clear out She is auctioning her stash of Lego on Ebay to raise a few bob for MS charity This links to the ebay list Lego theme   starting price Pirates  £10 to £100 Click here Castle £12 to £150 Click here Star Wars £8 to £20 Click here Airplanes £10 to £100 Click here Indiana Jones...

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