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Blood cells clearing up the myelin damage..

Zhou T, Zheng Y, Sun L, Badea SR, Jin Y, Liu Y, Rolfe AJ, Sun H, Wang X, Cheng Z, Huang Z, Zhao N, Sun X, Li J, Fan J, Lee C, Megraw TL, Wu W, Wang G, Ren Y. Microvascular endothelial cells engulf myelin debris and promote macrophage recruitment and fibrosis after neural injury. Nat Neurosci. 2019 Jan 21. doi: 10.1038/s41593-018-0324-9. [Epub ahead of print] The clearance of damaged...

Making new myelin, have animal studies been sending us in the wrong direction?

You all know that you can assess how old a tree is by counting the growth rings. You all have heard on carbon-dating, whereby you can assess the age of living things that have died. This works because living things are made of carbon containing molecules. Carbon comes in a radio-active form called carbon fourteen (related to the number of atoms and electrons in the molecule). This is decaying to...

Lumbar Puncture Headache…The answer is not age and sex…It’s your needle!

We have been talking about dinosaur neurologists and asking can they learn and change pratice? Prof G and DrRuth will be tearing their hair out with dispare on reading this. It will be disappointing that we are not listening and learning. Post-lumbar puncture headache: an adverse effect in multiple sclerosis work-up. Vecchio D, Naldi P, Ferro V, Comi C, Leone MA, Cantello R.Neurol Sci...

Think Hand but now see it

We have been talking about saving hand function, but can we get an understanding of why hand function. The imagers have been looking and they BACKGROUND:: Hand motor impairment has considerable effects on daily-life activities of patients with multiple sclerosis (pwMS). Understanding its anatomo-functional substrates is relevant to provide more specific therapeutic interventions...

January Q&A 2019

The New Year has arrived and Now has the Q&A post use it to ask those questions that are unrelated to the posts.

I have not put a snowy picture because in my Garden the buds are popping and the new leaves are arriving, I fear to be eaten by the next “Beast from the East”, so for the insomniacs or early risers, we have a lunar eclipse.

A quick summary of Prof G’s Twitter activity (17-23 Sept 2018)

If rapamycin works in MS does it mean the T-reg hypothesis is back on the table? I suspect not. #ResearchSpeak pic.twitter.com/tb6ODTluWn — Gavin Giovannoni (@GavinGiovannoni) September 18, 2018 More hype over substance! #ClinicSpeak Stem cell therapy for neurological disorders: A focus on aging. pic.twitter.com/zIQnUi5v3D — Gavin Giovannoni (@GavinGiovannoni) September 18, 2018 An interesting...

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