CategoryCOVID-19

#MSCOVID19: good news

Barts-MS rose-tinted-odometer: ★★★★★ The late late-breaking session at the MSVirtual2020 meeting, which covered COVID-19 has already received a lot of air-time on social media. The big-data alliance confirmed the Italian data, i.e. that people with MS (pwMS) on anti-CD20 are at higher risk of getting COVID-19 and severe COVID-19 (hospitalisation, intensive care admission and/or ventilation)...

MD2

ProfG wants the real MS to stand-up and asks about smouldering lesions. We think that hot microglia at the centre of these. A few years ago MD2 came up with the idea that antibodies within the oligoclonal bands could activate microglial by binding to receptors on the microglia and that may mean that it doesn’t matter what the antibodies are reactive against, so stop looking for anti-myelin...

#MSCOVID19 Will CD20 treatment make you into a shedder

Typically when infected with SARS-CoV-2, you make an immune response and you get rid of the virus. But if you do not have an effective immune sytstem you can’t get rid of the virus and you can become a super spreader. Here is an interesting case that is not MS, but if you are CD20 depleting and you get that dry cough, fever and loss of smell think about your fellow humans and self-isolate...

#MSCOVID19 running the talk

Barts-MS rose-tinted-odometer: ★★★★★ In anticipation of a second-lockdown at a meeting with colleagues last night I was asked the question about what positive experiences I could reflect on from the first lockdown. Firstly, no international travel and a focus on family, home life and the realisation that we can live more sustainably. Secondly, walking or running the talk. I decided to take my own...

#MSCOVID19: the new lepers?

Barts-MS rose-tinted-odometer: ★★★ Early this week my wife came down with a cold. Did she have coronavirus was the immediate question? She asked me for advice and I said she had better get herself swabbed and in the interim we should isolate ourselves. All she had was a mild headache (sinus-type), runny nose, sneezing and a sore throat. She did not have a temperature and only developed a mild...

#MSCOVID19: European COVID-19 Cup Quarterfinals

There has been a lot of debate about which country has had the best strategy at dealing with their coronavirus epidemic. It is clear based on the epidemiology of pandemics that countries needed to play with the mid and end game in mind. We are now quite a way into the COVID-19 pandemic and have reached the quarterfinals stage. Which countries do you think are going to win the quarterfinals and...

#MSCOVID19: round 2

Barts-MS rose-tinted-odometer: ★ Every now again it is worth covering a topic that is important for people living with MS (pwMS) a second time. Today’s topic is COVID-19 prehabilitation. Today when I got on the  London Underground to come to work the carriages were ~75% full, i.e. very few empty seats and not much standing room. In other words, adequate social distancing was not possible...

#MSCOVID19: has coronavirus cancelled the flu season?

Barts-MS rose-tinted-odometer: ★★★★★ I think COVID-19 has just cancelled the flu season.  I and many public health officials were very concerned that we were heading for a double-whammy this winter with a second and third surge of COVID-19 and a bad influenzae pandemic superimposed on it. It is looking like this may not happen. In the Southern hemisphere,  including my country South...

#MSCOVID19: transverse myelitis

Barts-MS rose-tinted-odometer: ★★ How do you distinguish transverse myelitis that is not MS-related from spinal cord involvement in MS?  Yesterday after reporting the possible and likely link between the Oxford-AstraZenca vaccine and transverse myelitis (TM) and possibly MS you asked how do neurologists differentiate TM from CIS or MS.  Idiopathic or post-infectious/vaccine-related TM...

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