CategoryCOVID-19

Detecting #MSCOVID19 infection. SPIN and SNOUT

Hello my name is Triska. I am working with DrAngry and ProfB and was due to do my student Lab project on anti-drug antibodies in MS. I have been told that the subject matter is top secret. However, things have changed and I have been doing a COVID-19 related study. You may know that you can detect the virus is you are infected. However, after you have been infected, you will make an anti-COVID-19...

COVID Breakfast: Can we get a Heineken Test?

Prof G is going to get a COVID blood test next week. Is he? isn’t he? This is what we will all be asking ourselves? Are we? Aren’t we? Have we been infected on not? This will depend on the test. Is it good enough? We need the Heiniken Test…What’s that? Well based on a Beer Advert about Refreshment, we need a Test that can “Reach the Parts that other Tests Cannot...

MS and Dogs

Dogs are being trained to sniff out Covid-19. But for many with MS, they’re already proven live-savers… By Rachel Horne There are two things which changed Janette Coombs life. One was a faceless, degenerative disease which raced through her body – stripping her of her mobility, her self-confidence and her independence. And the other? He has soft brown eyes, four legs and never leaves her...

#MSCOVID19 ocrelizumab

Roche is the first company to publish their data on how patients with MS are doing with COVID-19 who are being treated with ocrelizumab. Please note the data is on the first 100 cases that have been reported to Roche via their adverse event (AE) reporting mechanisms. Twenty-six of the cases have been reported as being severe with 5 being critical (see table below). These figures are pretty much...

#MSCOVID19 Boris Johnson is obese

Obesity has taken centre stage after Boris Johnson admitted that his recent coronavirus scare may have been related to his obesity. He is now pledging to do something about it. His sudden interest in the UK’s obesity problem is getting a lot of ink space in both the tabloids & broadsheets and airtime on radio & TV. Andrew Marr even covered it this morning on his BBC talk show. Will...

#MSCOVID19

COVID19 continues to appear to be influenced marginally if at all by MS-DMT and probably vice versa. We are starting to see the case reports and I know some registry data is on the way However the new epidemic is beginning to crank up . This is the publication epidemic and now it is over 500 new papers a day. It has become counter productive to try and keep up with it all. Most of them adding...

#MSCOVID19 super-superspreader

A single man triggered a massive contact tracing exercise in Seoul, South Korea, after visiting 5 nightclubs in a Seoul neighbourhood on a weekend and later tested positive for COVID-19. Not only does this case highlight the scope of the response which can be triggered by one infected individual but the willingness of Korean authorities to use mobile phone data, credit card data and CCTV footage...

#MSCOVID19 De-deployed

This is a very good news post and worth a quiet celebration.  As you can see from the study and figure below that Barts Health NHS Trust, where we work, was at the epicentre, of the epicentre of the UK’s COVID-19 pandemic. London has had the most COVID-19 cases in the UK and it looks as if the majority of cases where managed in our four COVID active hospitals. This graph shows just is how...

#MSCOVID19 Endemic musings

Fudging the issues or bumbling along is how the public, opposition politicians and the journalists are interpreting the Government’s handling of the exit strategy for the COVID-19 epidemic in the UK. I don’t agree. I think the Government has a clear plan, which is being driven primarily by economic considerations.  The primary objective of the lockdown was to protect the NHS and this has...

#MSCOVID19 It’s not all good news for anti-CD20

ProfG has written about the the effect of continous B cell depletion and the the influence of B cell depletion. However, this posts asked if continous B cell depletion can put you at risk of catching SARS-CoV-2 virus. Although B cells are important in fighting off bacteria, there is a small increased risk of catching some viral infections (Hauser et al. 2019). CD20 is expressed by the B cells...

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