Iron Rims image from Frontiers The characteristic feature of is multi-focal inflammatory activity; an infiltration of immune cells leading to loss of myelin and axons within these areas creating the appearance of round lesions. The natural evolution of these lesions like any area of injury in the rest of the body and shrink to a certain degree overtime. A fraction, however, continue to smoulder...
MS Vaccine
The development of COVID-19 and the rapid way that RNA vaccines have been developed means that you have a rapid way of developing vaccines against your viruses of choice. So which virus do you want to get rid off…The ones that cause warts Hope this doesn’t put you off your rice crispies this morning:-) Epstein Barr Virus? Well ProfGs wish is their command, maybe he can convince them...
If you have the Lumper’s you get the Splitters too. Can imaging spot the progressors
Diagnosis of Progressive Multiple Sclerosis From the Imaging PerspectiveA ReviewFilippi et al. JAMA Neurol 2020. doi:10.1001/jamaneurol.2020.4689 Importance Although magnetic resonance imaging (MRI) is useful for monitoring disease dissemination in space and over time and excluding multiple sclerosis (MS) mimics, there has been less application of MRI to progressive MS, including...
Anti-drug antibody awareness: HCP survey
Hello, my name is Farhana and I am a third year Biomedical Sciences student at Queen Mary University of London. I was born and brought up in Rome and moved to the UK when I was 12 where I completed my GCSE and A-Levels. After completing my degree, I am hoping to study medicine and become a doctor specialising in neuroscience or paediatrics. I am hoping work around the world as my ambition to...
Optic Neuritis App Development survey
Hello, my name is David and I’m a final year Biomedical Science student at Queen Mary University of London. I was born in Lagos, Nigeria and brought up in Middlesbrough, located in the north east of England. After my current degree I hope to study medicine and specialise as an ophthalmologist. My interest in ophthalmology grew as a result of my part time work at King’s College Hospital’s...
Guest Post:Cell Therapies to Treat Viral Infections
Today we are delighted to have a guest post by Dr Chris Lazarski to talk about their interesting work. Background: Vaccines are a critical tool to protect the majority of people from viral infection. However, some people require a more involved treatment strategy to treat persistent viral infections. These people may be immune suppressed because they have received a bone marrow...
An App to sniff out MS
Like a pig snouting truffles, can Artificial Intelligence diagnose MS? I used to think neurologists did this – one has a nose for these things 😉 The app uses a matrix involving a ‘mood questionnaire’ to figure out well being; ‘symbol matching’ to assess cognition; ‘walking’ using a step tracker; ‘u-turn’ assessing ability to turn;...
COVID-19 has changed neurology
I generally don’t like to rock the boat on anything, this applies to what I wear, eat, the people I co-locate with and work. It should therefore come as no surprise that my response to our changing practice if anything luke warm. I understand fully (more so than you may credit) the impact that COVID-19 has had on hospitals, and continues to do so. But, in my opinion this should be temporary...
Interogating MS with new technology, it’s a T & B cell co-operation thang.
With new technology is was not a question of if, but a question of when the protein production array of individual cells will be done, You can now look for the antigen-specific receptors of each cell to find out what they target is you can look at the proteins they make to say what cell types are there and this latter aspect was the focus of this study. They got the protein signatures...
Is telemedicine the future?
Medical care without leaving your home – has an attractive ring to it; but, one that has been a reality for many parts of the world where ease of access to healthcare has been an issue. For example, in Scotland, ‘Telestroke‘ was developed to allow acute stroke patients to be evaluated by a stroke specialist within the 4.5h thrombolysis window, remotely. Increasingly telemedicine...