Tagblood brain barrier dysfunction

Understanding the biology of paramagnetic rims in Multiple Sclerosis

Some of you may have not yet heard about paramagnetic rims in MS lesions. Their presence on MRI scans is felt to represent iron rich microglial inflammation in the brain occurring in a subset of individuals. Pathologically iron rims reflect slowly expanding chronically active MS lesions (see below). Figure: Paramagnetic lesion arrowed in (a) in a 34 y with RRMS. [Source-this article] The presence...



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