TagInterferon beta

What is end-organ damage?

Help! How do I manage progressive brain atrophy in a patient who is NEDA-3? End-organ damage is a catch-all phrase for the degeneration of the brain; it occurs as part of the ageing process that some consider pathological and others as a normal fact of life. I have hinted that I consider it both because end-organ damage is potentially modifiable via lifestyle modifications and pharmacological...

And the risk-sharing scheme results…

J Neurol Neurosurg Psychiatry. 2018 Sep 21. pii: jnnp-2018-318360. doi: 10.1136/jnnp-2018-318360. [Epub ahead of print] Assessing the long-term effectiveness of interferon-beta and glatiramer acetate in multiple sclerosis: final 10-year results from the UK multiple sclerosis risk-sharing scheme. Palace J, Duddy M, Lawton M, Bregenzer T, Zhu F, Boggild M, Piske B, Robertson NP, Oger J, Tremlett H...

Papers during the week

  Here are some papers you may or may not find interesting Whilst NICE no longer supports the use of CRAB drugs, this study does say that on first signs of MS, these agents work although it takes a few months to see this. So we wait to see what are the consequences of early intervention with a high activity agent. Problem is NICE has tied the hands of the neuro on this one. Maybe time to re...

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