Tagmacrophages

The far reaching arm of alemtuzumab

The immune system (image from Novus Biologicals) Whilst we talk about targeted B cell treatments, alemtuzumab possibly is what I’d term a ‘Domestos’ style drug. This type of drug is useful when your aim is to control the entire immune system quickly. Drugs similar to this are cyclophosphamide, cysclosporin and mitoxantrone; which are all considered highly active therapies. Many...

Chronic lesion activity in MS as seen on MRI

If you’d asked an year ago on whether I though MRI had a role beyond diagnosis in MS? My answer would have been an emphatic ‘NO’. The Achilles heel of MRI has always been the difficulty of standardizing scanning techniques to a large scale population level and adapting these accurately to work seamlessly during the day-to-day shortcomings of clinical imaging facilities within...

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